Deutivacaftor CAS 1413431-07-8

Product Description:

Khoom npe: Deutivacaftor CAS 1413431-07-8

 

Synonyms:

Ivacaftor deuterated 1413431-07-8;

CTP -656.

 

Chemical & Physical Properties

Cov tsos mob: Dawb rau Off-White khoom

Kev Ntsuas: NLT98%

Qhov ceev: 1.2g / cm3

Boiling Point: 550.5 degree ntawm 760 mmHg

Cov khoom siv tshuaj lom neeg: soluble hauv DMSO (me ntsis), Methanol (me ntsis, Kub)

 

Daim ntawv thov: Deutivacaftor yog lub zog CFTR modulator nrog EC50 tus nqi ntawm 255 nM rau CFTR txhim kho hauv G551D / F508del HBE cells.Ivacaftor-d9 yog qhov ncauj lus thiab hloov kho deuteride ntawm Ivacaftor siv rau hauv kev tshawb fawb cystic fibrosis.

 

Peb tseem tuaj yeem muab Deutivacaftor nruab nrab:

5-(1,1-dimethylethyl) salicylic acid 16094-31-8;

Benzoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]oxy]-5-(1,1-dimethylethyl)-, methyl ester 2342594-39-0;

2-bromo-4-(tert-butyl)-6-(2-(methyl-d3)propan-2-yl-1,1,1,3 ,3,{13}}d6)-3-nitrophenyl methyl carbonate 2342594-36-7.

 

 

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

 

 

Cov khoom raws li patent yog muab rau R & D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: deutivacaftor cas 1413431-07-8, manufacturers, lwm tus neeg, Hoobkas, yuav, Tshuag

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