Chenodeoxycholic Acid CAS 474-25-9

Khoom Piav Qhia:

Khoom Lub Npe: Chenodeoxycholic acid CAS TSIS TAU: 474-25-9

Lub ntsiab lus:

Cholan-24-oic acid, 3,7-dihydroxy-, (3α, 5β, 7α)-;

3α, 7α-Dihydroxy-5β-cholanic Acid;

anthropododesoxycholicacid;

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Dawb mus rau dawb-dawb crystalline hmoov

Kev Ntsuas: ≥99.00%

Ceev: 1.128g/cm3

Kub Point: 547.1 ℃ ntawm 760 mmHg

Melting Point: 167-171 ℃

Flash Point: 298.8 ℃

Refractive Index: 1.558

Dej Solubility: YUAV UA LI CAS YUAV TSUM TAU

Kev Cia Cia: Khaws cia rau qhov chaw txias, qhuav. Khaws rau hauv lub thawv kaw kaw.

Cov Ntaub Ntawv Kev Nyab Xeeb:

RTECS: FZ1980000

Cov Lus Hais Txog Kev Nyab Xeeb: S36/37-S45

HS Code: 2918990090

WGK Lub Tebchaws Yelemees: 2

Nqe Lus Risk: R63

Cov lej phom sij: Xn

Chenodeoxycholic acid (tseem hu ua chenodesoxycholic acid, chenocholic acid thiab 3α, 7α-dihydroxy-5β-cholan-24-oic acid) yog kua qaub. Nws tshwm sim raws li cov tshuaj dawb crystalline tsis yaj hauv dej tab sis yaj hauv cawv thiab acetic acid, nrog cov ntsiab lus melting ntawm 165-167 ° C. Cov ntsev ntawm cov carboxylic acid no hu ua chenodeoxycholates. Chenodeoxycholic acid yog ib qho ntawm cov kua tsib hauv lub cev ua los ntawm daim siab.

Nws yog thawj zaug cais los ntawm cov kua tsib ntawm cov goose hauv tsev, uas muab nws&"cheno &"; ib feem ntawm nws lub npe (Greek: χήν=goose).

Chenodeoxycholic acid thiab cholic acid yog ob yam kua tsib hauv tib neeg. Qee qhov lwm tus tsiaj muaj Muricholic acid lossis deoxycholic acid ntau dua li chenodeoxycholic acid.

Chenodeoxycholic acid tau tsim nyob rau hauv daim siab los ntawm cov roj (cholesterol) los ntawm cov txheej txheem uas cuam tshuam nrog ntau qib enzymatic. Ib yam li lwm cov kua qaub, nws tuaj yeem sib txuas hauv daim siab nrog taurine lossis glycine, tsim taurochenodeoxycholate lossis glycochenodeoxycholate. Conjugation ua rau qis pKa. Qhov no txhais tau hais tias cov kua qaub sib txuas tau sib xyaw ua ke ntawm cov pH ib txwm nyob hauv cov hnyuv thiab yuav nyob hauv txoj hnyuv kom txog thaum mus txog ileum qhov uas feem ntau yuav rov nqus tau. Cov kua qaub kua qaub tsim micelles uas pab txhawb kev zom cov lipid. Tom qab nqus tau, lawv raug coj los ntawm daim siab thiab rov ua dua, yog li nkag mus rau hauv kev nkag mus rau lub cev. Unabsorbed chenodeoxycholic acid tuaj yeem hloov pauv los ntawm cov kab mob hauv txoj hnyuv kom tsim cov kua tsib theem thib ob hu ua lithocholic acid.

Choendeoxycholic acid yog qhov muaj zog tshaj plaws ntawm cov kua tsib kua qaub ntawm kev txhawb nqa cov kua tsib kua qaub txais, farnesoid X receptor (FXR). Cov ntawv sau ntau ntawm cov noob tau qhib los ntawm FXR.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: chenodeoxycholic acid cas 474-25-9, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

• Tug: Pyrroloquinoline Quinone CAS 72909-34-3
• Tom ntej: TAUROURSODEOXYCHOLIC ACID CAS 14605-22-2