Hu rau:Errol Zhou (Mr.)
Tel: ntxiv 86-551-65523315
Mobile/WhatsApp: ntxiv 86 17705606359
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Email:sales@homesunshinepharma.com
Ntxiv:1002, Huanmao Tsev, No.105, Mengcheng Txoj kev, Hefei Lub zos, 230061 Tuam Tshoj
CAS TSIS TAU: 1035270-39-3
Cov mis mos molecular: C26H33N5O3
Molecular phaus: 463.57200
EINECS TSIS YOG: 681-057-4
MDL TSIS YOG: MFCD22580423
Khoom Piav Qhia:
Khoom Lub Npe: AZD-4547 CAS TSIS TAU: 1035270-39-3
Lub ntsiab lus:
N- [5- [2- (3,5-dimethoxyphenyl) ethyl] -1H-pyrazol-3-yl] -4-[(3R, 5S) -3,5-dimethylpiperazin-1-yl] benzamide;
QCR-89;
Tshuaj& Lub Cev Muaj Zog:
Tshwm sim: Crystalline khoom
Kev Ntsuas: ≥98.0%
Ceev: 1.189
Cov Kub Kub: 621.7 ± 55.0 ℃ (Kwv yees)
PKa: 13.66 ± 0.10 (kwv yees)
Flash Point: 329.8 ± 31.5 ℃
Vapor Siab: 0.0 ± 1.8 mmHg ntawm 25 ℃
Index ntawm Refraction: 1.602
AZD4547 yog bioavailable, muaj zog, thiab xaiv tus inhibitor ntawm fibroblast kev loj hlob tau txais (FGFR) tyrosine kinases. AZD4547 muaj txiaj ntsig tshwj xeeb hauv kev tiv thaiv FGFR1, 2, thiab 3 tyrosine kinases thiab tseem tab tom tshawb fawb soj ntsuam rau kev kho FGFR cov qog. AZD4547 yog qhov kev xaiv tshiab FGFR inhibitor lub hom phiaj FGFR1/2/3 nrog IC50 ntawm 0.2 nM/2.5 nM/1.8 nM hauv kev tshuaj ntsuam tsis pub dawb ntawm tes, kev ua haujlwm tsis muaj zog tiv thaiv FGFR4, VEGFR2 (KDR), thiab kev ua haujlwm me me pom ntawm IGFR, CDK2, thiab p38 ua. Theem 2/3.
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.
Cim npe nrov: azd-4547 cas 1035270-39-3, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag
