Kev faib tawm ntawm APIs

Raws li nws cov peev txheej, APIs tau muab faib ua ob pawg loj: cov tshuaj siv hluavtaws thiab tshuaj siv hauv tshuaj.

Cov tshuaj tua hluavtaws muaj peev xwm raug muab faib ua tshuaj ntxiv rau cov tshuaj tua hluavtaws thiab cov tshuaj siv hluavtaws organic. Inorganic hluavtaws cov tshuaj yog cov sib xyaw ua ke (muaj tsawg lub ntsiab lus), xws li txhuas hydroxide thiab magnesium trisilicate rau kev kho mob ntawm lub plab zom mov thiab duodenal mob; cov tshuaj siv hluavtaws organic yog tsim los ntawm cov khoom siv tshuaj organic yooj yim, los ntawm cov tshuaj ntawm cov organic ua los ntawm cov tshuaj lom neeg (xws li tshuaj aspirin, chloramphenicol, caffeine, thiab lwm yam).

Cov tshuaj lom neeg muaj peev xwm tau muab faib ua cov tshuaj biochemical thiab phytochemical tshuaj raws li lawv qhov chaw. Cov tshuaj tua kab mob feem ntau ua los ntawm microbial fermentation thiab yog rau cov qeb ntawm biochemistry. Ntau yam ntawm cov tshuaj tiv thaiv ib nrab hluavtaws uas tau tshwm sim nyob rau xyoo tas los no yog cov khoom sib txuas ntawm biosynthesis thiab tshuaj lom neeg. Ntawm cov APIs, qhov sib npaug ntawm cov tshuaj tua kab mob organic, cov khoom lag luam tawm thiab cov txiaj ntsig tawm yog qhov loj tshaj plaws, uas yog lub hauv paus tseem ceeb ntawm kev lag luam tshuaj lom neeg. Qhov zoo ntawm cov ntaub ntawv raw txiav txim siab qhov zoo ntawm kev npaj ua. Yog li, cov qauv ua tau zoo yog nruj heev. Cov teb chaws thoob ntiaj teb tau tsim cov qauv tshuaj lub teb chaws nruj thiab cov txheej txheem tswj kev ua haujlwm zoo rau lawv qhov kev siv APIs.