Mob Cancer: Vitamin D tuaj yeem qhib lub kaus los tiv thaiv kev kho mob cancer nrov tshaj plaws

Noj tshuaj vitamin D pab tiv thaiv kom tsis txhob muaj mob tshwm sim ntau los ntawm kev kho mob cancer

Kev siv tshuaj kho mob qog nqaij hlav cancer yog lub npe hu ua koob thib 3 hauv kev kho mob qog noj ntshav. Raws li kev kho mob cancer kub tshaj plaws, nws tsis vam khom cov tshuaj los tua cov qog noj ntshav, tab sis rau tib neeg mob qog nqaij hlav ntshav los ntawm nws lub cev tiv thaiv kab mob. Txawm li cas los xij, txawm hais tias hom no tau pab ntau tus neeg mob kom ntev lawv lub neej, nws kuj tseem" ua tsis raug" tib neeg cov ntaub so ntswg thiab ua rau muaj mob nrog rau mob caj dab.

Thaum Lub Rau Hli 22, cov ntawv tshawb fawb tshaj tawm los ntawm American Cancer Society (ACS) cov phooj ywg rov ntsuam xyuas phau ntawv xov xwm" Cancer Cancer" (cuam tshuam cuam tshuam: 5.238) muab" ntsuas phoo&zoo; ntawm kev siv tshuaj tua kab mob cancer.

Ib pab neeg tshawb fawb ntawm Tsev Kawm Ntawv Kho Mob Harvard tau pom tias kev noj tshuaj pab vitamin D tuaj yeem pab tiv thaiv kev phiv los ntawm kev tiv thaiv kab mob cancer. Qhov no kuj yog thawj zaug tshawb nrhiav kom paub cov vitamin D los ua ib qho kev tiv thaiv tiv thaiv colitis los ntawm kev siv tshuaj tiv thaiv kab mob.

https://doi.org/10.1002/cncr.32966

Osama Rahma, MD, Dana-Farber Cancer Institute, Harvard Medical School, tau hais tias:" Kev mob caj dab los ntawm kev txhaj tshuaj tiv thaiv qog yuav txwv kev siv txoj kev cawm neeg no thiab ua rau muaj kev kho mob. Txawm hais tias kev mob plab yog qhov ntau thiab feem ntau ntawm kev tiv thaiv kab mob cancer yog ib qho ntawm qhov tshwm sim, tab sis tam sim no tib neeg tseem paub tsawg heev txog cov kev xaiv uas tuaj yeem siv los tiv thaiv cov kev mob tshwm sim no."

Hauv xyoo 2008, daim ntawv qhia tshawb fawb luam tawm los ntawm" Qhov Chaw Ntsuam Xyuas Kev Ua Zoo Rheumatology" tawm tswv yim tias tus kab mob autoimmune thiab mob hnyuv, vitamin D yuav cuam tshuam rau lub cev tiv thaiv kab mob. Txhawm rau soj ntsuam seb vitamin D puas muaj peev xwm txo qis tus neeg mob' kev pheej hmoo ntawm colitis ntxias los ntawm kev siv tshuaj kho mob, Rahma thiab cov npoj yaig tau npaj los pib kev kawm.

Ntawm 2011 thiab 2017, 213 tus neeg mob melanoma tau txais tsawg kawg ib chav pembrolizumab, nivolumab, ipilimumab, lossis kev sib txuas ntawm ipilimumab thiab nivolumab (cov tshuaj tiv thaiv kab mob hauv lub cev). 66 ntawm cov neeg mob no tau noj tshuaj vitamin D ua ntej kho. Thaum kawg, 37 tus neeg mob tau tshawb pom tseeb tias muaj mob caj dab.

Kawm txog kev tshwm sim ntawm kev mob plab raws li kev tiv thaiv kab mob qog ua kab mob rau lub cev

Multivariate regression pom tias cov neeg mob noj cov vitamin D muaj 65% txo hauv plab. Qhov kev tshawb pom no tau txheeb xyuas qhov tseeb hauv kev tshawb nrhiav tom ntej. Ntawm 169 tus neeg mob melanoma tau txais kev kho mob hauv Massachusetts General Hospital, 49 muaj mob plab, thiab cov uas tau noj tshuaj vitamin D muaj 54% txo cov mob hlwb.

Multivariate logistic regression tsom xam ntawm cov kev pheej hmoo ntawm colitis

Tsis tsuas yog nws tiv thaiv kev phiv los ntawm kev siv tshuaj kho mob cancer, vitamin D kuj tseem pab cov neeg mob uas tiv thaiv mob qog noj ntshav. Thaum lub Tsib Hlis 30th, cov kws tshawb nrhiav los ntawm University of Eastern Finland thiab University Autonomous University of Madrid tau tshaj tawm cov ntawv sau rov qab los ntawm" Seminars hauv Cancer Biology", qhia tias qhov tseem ceeb ntawm cov vitamin D yog qhov zoo rau kev tiv thaiv qog noj ntshav thiab mob ntshav siab. ntawm qee cov qog nqaij hlav. Cov nyhuv los tiv thaiv mob qog noj ntshav ntawm cov vitamin D yog pom tseeb tshwj xeeb hauv kev tiv thaiv thiab kho mob nyuv thiab mob cancer ntshav. Tsis tas li ntawd, qhov ua siab loj ntawm cov vitamin D tej zaum yuav cuam tshuam nrog kev phom sij me dua, tab sis qhov kev cuam tshuam no txawv ntawm ib tug neeg mus rau lwm tus.

https: //doi.org/10.1016/j.semcancer.2020.05.018

Hauv ntej, txoj kev tshawb nrhiav tshiab no qhia tau hais tias kev noj cov tshuaj vitamin D ua ntej pib siv tshuaj tiv thaiv qog noj ntshav yuav pab cov neeg mob tawm tsam cov kev mob tshwm sim los ntawm nws. Kev tshawb nrhiav pom yav tom ntej tseem tseem xav tau los soj ntsuam seb puas tsim nyog tau txais cov tshuaj vitamin D kom muaj kev nyab xeeb, npaj tau yooj yim, thiab siv txoj hauv kev los tiv thaiv kev haus tshuaj lom rau lub plab ua kom lub plab thiab nthuav tawm cov kev kuaj mob qog noj ntshav.