AstraZeneca cov tshuaj CLL Calquence tau pom zoo los ntawm NICE hauv UK

Ob peb hnub dhau los, National Institute of Health thiab Clinical Optimization (NICE) hauv tebchaws Askiv tau txiav txim siab pom zoo AstraZeneca's BTK inhibitor Calquence (Acalabrutinib) rau hauv British National Health Service (NHS) rau kev kho qee tus neeg laus mob lymphocytic leukemia (CLL) )). Cov tshuaj tau dhau los ua thawj lub hom phiaj kho qhov ncauj rau cov neeg mob Askiv uas muaj cov roj ntsha lymphocytic (CLL) uas tsis tuaj yeem raug kho nrog thawj kab kev kho mob.

Raws li tsab ntawv pom zoo cov lus pom zoo muab los ntawm British ntxawg koom haum, cov tshuaj tau pom zoo rau lub Kaum Ob Hlis xyoo tas los rau kev kho mob ntawm cov neeg mob CLL nrog rau 17p tshem tawm lossis TP53 hloov pauv, lossis fludarabine ua ke nrog cyclophosphamide thiab rituximab (FCR), thiab khoovamustine ua ke nrog rituximab (BR). Siv tau rau cov neeg mob CLL. Cov kws tshaj lij uas koom nrog hauv NICE Tshuaj Pab Pawg Kho Mob tau hais ntxiv tias Calquence zoo siab rau thiab muaj cov kev mob tshwm sim tsawg dua piv nrog kev kho CLL tam sim no.

Calquence' s NICE kev pom zoo hauv tebchaws Askiv yuav muab cov neeg mob no nrog txoj kev kho mob tshiab uas tsis yog kev siv tshuaj kho mob, uas tshwj xeeb tshaj yog pab tau thaum lub sij hawm THAWJ-muaj thoob qhov txhia. Cov neeg mob cuam tshuam los ntawm tus mob khaub thuas no feem ntau nws tsis yooj yim mus rau hauv tsev kho mob ntau zaus. Cov. Cov xwm txheej tam sim no paub tias lub thawv 30-hnub ntawm 100 mg Calquence ntsiav tshuaj yog tus nqi 5,059 phaus (kwv yees RMB 45,766), tab sis AstraZeneca thaum kawg yuav muag cov tshuaj rau British NHS ntawm tus nqi txo ntawm qhov no. Cov.

Thaum Lub Kaum Ib Hlis xyoo tas los, European Medicines Agency (EMA) tau pom zoo Calquence raws li kev kho mob lossis kev sib koom tes nrog Roche Gazyvaro (obinutuzumab) rau yav tas los tsis kho thiab rov kho lossis rov kho lossis rov kho dua cov neeg mob CLL. Tebchaws Askiv NICE tau hais tias “vim tias lub tuam txhab tsis tau xa cov ntaub ntawv hais txog kev sib txuas ua ke no