Tovoraphenib CAS 1096708-71-2

Product Description:

Khoom npe: Tovoraphenib CAS 1096708-71-2

 

Synonyms:

2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide

TSI 2480-

 

Chemical & Physical Properties

Qhov tsos: Dawb Khoom

Kev Ntsuas: NLT98%

Melting Point: 197-199 degree

Boiling Point: 585.3℃(lit.)

Qhov ceev: 1.640g / cm3

pKa: 10.07 Nws

 

Daim ntawv thov:

MLN2480 nthuav tawm cov tshuaj tiv thaiv kab mob hauv cov qauv xenograft ntawm melanoma, mob qog noj ntshav, mob ntsws, thiab mob qog noj ntshav. MLN2480 (37.5 mg / kg) tau txais txiaj ntsig zoo hauv cov qauv qog xenograft. Kev sib xyaw ua ke ntawm MLN-2480 (12.5 mg) thiab TAK-733 (1 mg / kg) muaj txiaj ntsig zoo hauv SK-MEL-30 xenograft qauv, qhov kev kho mob monotherapy nrog tus neeg sawv cev ib leeg qhia qhov ua tau zoo heev.

 

 

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

 

 

Cov khoom raws li patent yog muab rau R & D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: Tovoraphenib CAS 1096708-71-2, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, hauv Tshuag

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