Tert-Butyl 4- [4- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrazol-1-yl] piperidine-1-carboxylate CAS 877399-74- 1

Khoom Qhia:

Khoom npe: tert-Butyl 4- [4- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrazol-1-yl] piperidine-1-carboxylate CAS 877399 -74-1

Txhais:

4- [4- (4,4,5,5-tetramethyl- [1,3,2] dioxaborolan-2-yl) -pyrazol-1-yl] -piperidin-1-carboxylic acid tert-butyl ester;

Tshuaj& Cov Khoom Uas Lub Cev:

Zog: cov hmoov dawb dawb

Ntsuas: ≥99.0%

Qhov ceev: 1.14g / cm3

Lub Ntsiab Kub: 492.8 ℃ ntawm 760 mmHg

Flash Point: 251.8 ℃

Crizotinib nrab.

Crizotinib yog ib qho me me molecule tyrosine kinase inhibitor (TKI) uas tsom rau tus mob qog rau lub cev (ALK), ROS1, thiab lwm oncogene receptor tyrosine kinase MET. Crizotinib tsiav tshuaj tuaj yeem siv rau kev kho mob hauv zos hauv cheeb tsam lossis metastatic tsis yog mob qog nqaij hlav ntsws tsis muaj mob ntsws me me (NSCLC) cov neeg mob uas ua rau zoo rau cov mob qog ntshav tsis txaus (ALK) txiav txim los ntawm SFDA-pom zoo kuaj cov qauv. Kev pom zoo los ntawm cov ntawv pov thawj no feem ntau yog xam raws lub hom phiaj teb cov lus teb (ORR) thiab cov pov thawj tsis muaj kev vam meej (PFS). Nyob rau tam sim no, tsis muaj pov thawj ntawm kev pab cawm (OS) ntawm cov khoom no.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov hu rau peb!

Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: tert-butyl 4- [4- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1h-pyrazol-1-yl] piperidine-1-carboxylate cas 877399-74- 1, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

• Tug: Tert-butyl 4- (4-iodo-1H-pyrazol-1-yl) piperidine-1-carboxylate CAS 877399-73-0
• Tom ntej: Crizotinib CAS 877399-52-5