Dorzolamide HCl CAS TSIS TAU: 130693-82-2

Khoom Piav Qhia

Khoom npe: Dorzolamide HCl CAS TSIS TAU: 130693-82-2

Txhais:

(4 S, 6 S) - 4 - (ethylamino) - 6 - methyl-5, 6 - dihydro - 4 H -thieno [2, 3-b] thiopyran - 2 - sulfonamide 7, 7-dioxide hydrochloride;

4 H-Thieno [2, 3-b] thiopyran - 2 - sulfonamide, 4 - (ethylamino) -5, {{{{1 5}} 3}} - dihydro - {{{{{16-}} 5}} 3}} - methyl -, {{{{{16-}} 5}} 0}}, 7-dioxide, ({ {0}} S, {{{1 5}} 3}} S) -, hydrochloride ({{1 5}}: {{{{16} 5}});

Dorzolamide hydrochloride;

(4 S, {{{1 3}}}} S) - 4 - (Ethylamino) - {{{{{14 {} 3}}}} - methyl-5, {{{1 3}}} - dihydro - 4 H-thieno [2, 3-b] thiopyran - 2 - sulfonamide { {{{1 3}}, {{1 3}},}, 7-dioxide hydrochloride ({{1 3}}: {{1 3}} );

(4 S, 6 S) - 4 - (Ethylamino) -5, 6 - dihydro - 6 - methyl - 4 H -thieno (2, 3-b) thiopyran - 2 - sulfonamide 7, 7-dioxide, monohydrochloride;

(4 S, 6 S) - 4 - (Ethylamino) - 6 - methyl-5, 6 - dihydro - 4 H -thieno [2, 3-b] thiopyran - 2 - sulfonamid-7,7-dioxidhydrochlorid;

4 H-thieno [2, 3-b] thiopyran - 2 - sulfonamide, 4 - (ethylamino) -5, 6 - dihydro- { {13}} - methyl -, 7, 7 - dioxide, (4 S, 6 S) -, monohydrochloride;

Tshuaj& Lub cev nqaij daim tawv

Zog: Dawb kom dawb-dawb hmoov

Ntsuas: ≥ 99. 0%

Ntom: 1. 53 g / cm 3

Lub Hauv Boiling Point: 575. 8 ℃ ntawm 760 mmHg

Melting Point: 265-267 ℃

Flash Point: 302 ℃

Solubility: Soluble nyob rau hauv dej, me ntsis soluble hauv methanol, soluble me ntsis nyob rau hauv anhydrous ethanol.

Dorzolamide Hcl (L 671152 Hcl; MK 507 Hcl) yog ib qho tshuaj tiv thaiv kab mob siab, uas yog carbonic anhydrase inhibitor.Target: carbonic anhydrase (CA) Dorzolamide hydrochloride yog carbonic anhydrase inhibitor. Nws yog cov neeg ua haujlwm tawm tsam lub ntsej muag, thiab ua los ntawm kev txo qis ntawm cov aqueous kev lom zem. Glaucoma tau ntxias hauv txoj cai qhov muag ntawm tus neeg laus Wistar nas los ntawm kev mob txhaws ntswg. Ib pawg sim yog muab tshuaj dorzolamide hydrochloride 2% - timolol 0. Pawg tswj tau muaj cov kev phais mob yam tsis muaj kev tswj hwm tshuaj. Daim ntawv thov tshuaj tau pib los ntawm 2 lis piam ua ntej kev phais mob (Pawg A), txij hnub phais (Pawg B), 2 lub lis piam tom qab phais (Pawg C), lossis 4 lis piam tom qab phais mob (Pawg D). RGC tau raug sau npe los ntawm kev txhaj tshuaj fluorogold thiab suav los ntawm kev npaj tiaj tiaj, thiab IOP raug ntsuas siv Tonopen. Ob qho dorzolamide-timolol ua ke thiab dorzolamide hydrochloride, thaum siv tshuaj pleev, txo IOP thiab txhim kho RGC ntau qhov kev ntsuas hauv kev sim thaum piv rau kev tswj qhov muag. Thaum pib ua ntej, nrog rau ncua sijhawm ntev dua ntawm kev thov tshuaj, ua rau RGC ntau dua [2]. Cov kev soj ntsuam: Glaucoma; Ocular hypertensionFDA Pom zoo Hnub: 199 5.

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Cim npe nrov: dorzolamide hcl cas tsis yog: 130693-82-2, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

• Tug: Brinzolamide CAS 138890-62-7
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