Pramlintide Acetate CAS 196078-30-5

Khoom Piav Qhia:

Khoom Lub Npe: Pramlintide acetate CAS TSIS TAU: 196078-30-5

Lub ntsiab lus:

pramlintide acetate hydrate;

25-L-Proline-28-L-proline-29-L-proline-aMylin (huMan) Acetate Hydrate;

Tripo-aMylin Acetate Hydrate;

Tshuaj& Lub Cev Muaj Zog:

Tsos: Dawb hmoov

Kev Ntsuas: ≥99.00%

Lub Sijhawm Ntev Cia: Khaws ntawm chav sov

Melting Point:> 175 ℃ (dec.)

Cia: Tub yees

Solubility: Acetic Acid (Me ntsis), DMSO (Me ntsis)

Cov Ntaub Ntawv Kev Nyab Xeeb:

Lo Lus Teeb: Ceeb Toom

Cov Lus Qhia Teeb Meem: H315; H319; H335

Cov lus ceeb toom ceev faj:

P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Qhov sib piv ntawm tib neeg amylin siv hauv kev kho mob insulin vam khom ntshav qab zib. Pramlintide acetate yog kev txhaj tshuaj tib neeg amylin analog uas tau tsim los rau kev kho mob ntshav qab zib hom 1 thiab hom 2, nrog rau insulin. Thaum nws tseem yog 37-amino acid peptide, nws txawv ntawm nws niam txiv ua ntej los ntawm kev hloov ntawm Ala-25, Ser-28, thiab Ser-29 nrog prolines. Tsis yog tsuas yog ua cov kev hloov kho no txhawm rau txhim kho cov peptide solubility, lawv tseem tshem tawm cov kev sib sau ua ke nrog amylin, ua rau muaj kev sib xyaw ua ke ruaj khov nrog kev khaws cia ntawm kev ua haujlwm lom uas tsim nyog rau kev siv tshuaj. Raws li qhov qhia tau ntawm lub zog, Pramlintide acetate txwv qhov kev khi ntawm cov xov tooj cua uas tsis muaj amylin rau nas nucleus accumbens daim nyias nyias nrog Ki tus nqi ntawm 23 pM. Nws cov txheej txheem ntawm kev ua raws li amylin; raws li neurohormone uas tau txiav txim siab nrog insulin los ntawm cov txiav ua kab mob β hlwb hauv kev teb rau cov pluas noj, nws koom nrog hauv cov piam thaj homeostasis. Ob qho tib si peptides qis dua qib qab zib los ntawm kev txwv tsis pub glucagon thiab los ntawm kev txwv tsis pub tus vagus-nruab nrab tus nqi ntawm lub plab tso tawm, yog li, qeeb hauv plab zom zaub mov carbohydrate. Tsis tas li ntawd, amylin, lossisPramlintide acetate, muaj qhov txiaj ntsig ntxiv ntawm kev ua kom lub cev tsis txaus siab tom qab ua rau poob phaus hauv cov neeg mob ntshav qab zib hom 2. Txij li Pramlintide acetate ua rau lub plab zom mov qeeb, nws tau txwv tsis pub siv rau cov neeg mob uas mob plab zom mov thiab hauv cov neeg mob noj tshuaj uas hloov pauv lub plab zom mov (cov tshuaj anticholinergic, xws li, atropine) lossis qeeb lub plab zom mov ntawm cov as-ham (xws li α-glucosidase inhibitors). Pramlintide acetate kuj tseem txwv tsis pub siv rau cov neeg mob uas muaj cov yam ntxwv hypoglycemic; vim kev sib koom ua ke nrog cov tshuaj insulin, kev tsim cov tshuaj insulin hnyav hypoglycemia yog qhov pheej hmoo. Feem ntau tau tshaj tawm cov xwm txheej tsis zoo suav nrog xeev siab, ntuav, tsis nco qab, mob taub hau, mob plab, nkees, kiv taub hau, hnoos, thiab pharyngitis.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: pramlintide acetate cas 196078-30-5, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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