Plitidepsin CAS 137219-37-5

Product Description:

Khoom npe: Plitidepsin CAS NO: 137219-37-5

Synonyms:

(2S)-N-(2R)-1-(3S,6S,8S,12S,13R,16S,17R,20S ,23S)-13-(2S)-butan-2-yl-12-hydroxy-20-(4-methoxyphenyl)methyl-6,17,21-trimethyl-3-(2-methylpropyl)-2 5,7,10,15,19,22-heptaoxo-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo21.3.0hexacosan-16-ylamino-4-methyl- 1-oxopentan-2-yl-N-methyl-1-(2-oxopropanoyl) pyrrolidine-2-carboxamide; Plitidepsin;

2-9-Didemnin B, 2-(1-(1,2-dioxopropyl)-L-proline)-;

Chemical Physical Properties:

Qhov tsos: Khoom

Assay: Ntau dua lossis sib npaug rau 99.0 feem pua

Qhov ceev: 1.24g / cm3

Refractive Index: 1.567

Plitidepsin (tseem hu ua dehydrodidemnin B, ua lag luam los ntawm PharmaMar, SA nyob rau hauv lub npe lag luam Aplidin) yog cov tshuaj sib xyaw uas muab rho tawm los ntawm ascidian Aplidium albicans. Tam sim no nws tab tom tab tom sim tshuaj ntsuam xyuas. Nws yog ib tug tswv cuab ntawm chav kawm ntawm cov tebchaw hu ua Didemnins. Plitidepsin yog cyclic depsipeptide uas yog thawj zaug cais tawm ntawm Mediterranean marine tunicate (Aplidium albicans) thiab, tam sim no, yog tsim los ntawm tag nrho cov synthesis thiab coj mus muag li Aplidin? Nws cov haujlwm antitumor, pom nyob rau hauv preclinical hauv vitro thiab hauv vivo kev tshawb fawb tau ua rau muaj ntau yam kev sim tshuaj uas tau ua nyob rau 17 xyoo dhau los, ib leeg lossis ua ke nrog lwm cov tshuaj tiv thaiv kab mob.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom raws li patent yog muab rau RD lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: Plitidepsin CAS 137219-37-5, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, hauv Tshuag

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