Glycoursodeoxycholic Acid CAS 64480-66-6

Product Description:

Khoom npe: Glycoursodeoxycholic Acid CAS 64480-66-6

Synonyms:

3..,7.beta.-Dihydroxy-5.beta.-cholanoylglycine;

N-(3..,7.beta.-Dihydroxy-5.beta.-cholan-24-}oyl)glycine;

N-[(3..,5.beta.,7.beta.)-3,7-Dihyd.

Chemical & Physical Properties

Tsos: Dawb rau Yuav luag dawb hmoov rau siv lead ua

Kev Ntsuas: NLT98%

Melting Point: 232-235 degree

Cov khoom siv tshuaj: Soluble hauv DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml; Ethanol: 1 mg

Daim ntawv thov: Glycoursodeoxycholic Acid (GUDCA) yog cov kua tsib tseem ceeb uas tshwm sim los ntawm cov metabolite ntawm Ursodeoxycholic Acid, uas yog siv los ua cov tshuaj tua kab mob. Raws li cov kua tsib acid thib ob, GUDCA pib los ntawm kev hloov pauv ntawm chenodeoxycholic acid (CDCA) los ntawm cov kab mob hauv plab hnyuv thiab tuav txoj haujlwm tseem ceeb hauv cov kua tsib kua qaub ntawm tib neeg thiab lwm yam tsiaj txhu, pab txhawb rau ntau yam txheej txheem physiological. Nws suav tias yog lub luag haujlwm tseem ceeb hauv cov kab mob enterohepatic, uas tswj kev nqus thiab tshem tawm ntawm cov kua tsib acids, thiab tau dhau los ua cov kev tshawb fawb hauv chav kuaj, nrhiav kev siv hluav taws xob thoob plaws ntau hom kev siv. GUDCA ua haujlwm ua tus agonist ntawm farnesoid X receptor (FXR), ib qho tseem ceeb ntawm cov receptors hauv kev tswj cov kua tsib acid homeostasis. Los ntawm kev khi thiab ua kom muaj zog ntawm FXR, GUDCA cuam tshuam cov kev ua haujlwm ntawm FXR, yog li hloov cov noob koom nrog hauv cov kua tsib acid metabolism thiab thauj. Tsis tas li ntawd, GUDCA nthuav tawm lub peev xwm los hloov kho cov haujlwm ntawm ntau cov enzymes cuam tshuam nrog lipid metabolism, suav nrog lipoprotein lipase, acyl-coenzyme A synthetase, thiab acyl-CoA oxidase. Nws kuj tseem ua rau muaj kev cuam tshuam los ntawm kev qhia cov noob cuam tshuam hauv cov metabolism ntawm lipids, carbohydrates, thiab cov protein. Tsis tas li ntawd, GUDCA qhia txog cov tshuaj tiv thaiv kab mob, tiv thaiv apoptotic, thiab cov haujlwm antioxidant.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom raws li patent yog muab rau R & D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: glycoursodeoxycholic acid cas 64480-66-6, manufacturers, lwm tus neeg, Hoobkas, yuav, Tshuag

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