Elinzanetant CAS 929046-33-3

Product Description:

Khoom npe: elinzanetant CAS 929046-33-3

 

Synonyms:

N-[6-[(7S,9aS)-7-(hydroxymethyl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2, 1-c][1,4]oxazin-8-yl]{19}}( 4-fluoro-2-methylphenyl)pyridin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide;

 

Chemical & Physical Properties:

Cov tsos mob: dawb mus rau lub teeb daj hmoov

Assay: Ntau dua lossis sib npaug rau 99.0%

Kub taw tes: 672.1 ± 55. 0 degree ntawm 760 mmHg

Flash Point: 360.3 ± 31.5 degree

Qhov ceev: 1.4g / cm3

Solubility: Soluble hauv DMSO 100mg / ml

 

 

Siv

Elinzanetant yog ib qho bioavailable neurokinin/tachykinin 1 receptor (NK1-receptor; NK1R; NK-1R) thiab NK3 receptor (NK-3R; NK3R)) antagonist, uas tej zaum yuav siv los kho. Cov tsos mob vasomotor hauv cov poj niam cev xeeb tub. Raws li kev tswj hwm qhov ncauj, elinzanetant lub hom phiaj, sib tw khi rau thiab thaiv cov haujlwm ntawm NK1R thiab NK3R hauv lub hauv nruab nrab paj hlwb (CNS), yog li inhibiting kev khi ntawm endogenous ligands thiab neuropeptides tshuaj P (SP; neurokinin-1; NK1) thiab neurokinin B (NKB). Qhov no inhibits NK1R / NK3R-mediated signal transduction thiab tej zaum yuav tiv thaiv tej yam mob menopausal xws li kub flashes. Neurokinin-mediated signaling yuav nce thaum lub sij hawm tsis muaj cov tshuaj hormones thiab yuav ua rau kub flashes.

 

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

 

 

Cov khoom raws li patent yog muab rau R & D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: elinzanetant cas 929046-33-3, manufacturers, lwm tus neeg, Hoobkas, yuav, Tshuag

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