Allopurinol CAS 315-30-0

Khoom Piav Qhia

Khoom npe: Allopurinol CAS TSIS: 315-30-0

Txhais:

Pural; Apurin; 4-HPP; Anzief; HPP;

1H-Pyrazolo [3,4-d] pyrimidin-4 (5H) -one;

4H-Pyrazolo [3,4-d] pyrimidin-4-ib, 1,5-dihydro-;

aloral; 4-Hydroxypyrazolo [3,4-d] pyrimidine;

Apurol; Allopurinol; Rho Tawm; Urbol;

1H-Pyrazolo [3,4-d] pyrimidin-4-ol;

1H-Pyrazolo (3,4-d) pyrimidin-4-ol (4-Hydroxypyrazolo (3,4-d) pyrimidine;

allopurinal;

Tshuaj & Lub Cev Lub Cev

Zog: Dawb rau Off-White hmoov

Assay: ≥99.0%, GMP / DMF

Cov Ntaub Ntawv Kev Nyab Xeeb

Allopurinol, muag nyob hauv cov npe lag luam Zyloprim thiab generics, yog cov tshuaj siv feem ntau los kho cov uric acid nyob rau hauv cov ntshav thiab nws cov teeb meem, suav nrog mob gout. Nws yog xanthine oxidase inhibitor thiab muab tshuaj rau qhov ncauj.

Nws nyob ntawm World Health Organization's Daim Ntawv Teev Cov Tshuaj Tseem Ceeb, cov npe tshuaj tseem ceeb tshaj plaws nyob rau hauv cov hauv paus pib noj qab haus huv

Allopurinol (Zyloprim) yog ib hom tshuaj xanthine oxidase inhibitor nrog IC50 ntawm 7.82 ± 0.12 μM.Target: XAOAllopurinol (Zyloprim, thiab generics) yog ib qho tshuaj uas siv los kho hyperuricemia (tshaj uric acid hauv ntshav ntshav) thiab nws cov teeb meem, suav nrog kev mob gout ntev. Cov. Nws yog xanthine oxidase inhibitor uas tau siv hauv ncauj. Ib qho kev nkag siab tsis meej yog tias allopurinol yog metabolized los ntawm nws lub hom phiaj, xanthine oxidase, tab sis qhov kev nqis tes no yog ua thawj coj los ntawm Aldehyde oxidase. Kev nquag metabolite ntawm allopurinol yog oxypurinol, uas kuj yog ib qho inhibitor ntawm xanthine oxidase. Allopurinol yuav luag tag nrho cov tshuaj rau oxypurinol hauv ob teev ntawm kev tswj hwm qhov ncauj, hos oxypurinol maj mam ua kom lub raum ntws dhau 18-30 teev. Vim li no, oxypurinol ntseeg tau feem ntau ntawm allopurinol cov nyhuv.Allopurinol yog purine analog; nws yog cov yam ntxwv ntawm isomer ntawm hypoxanthine (ib txwm muaj purine hauv lub cev) thiab nws yog ib qho inhibitor ntawm cov enzyme xanthine oxidase. Ntxiv rau kev thaiv cov qoob loo uric acid ntau lawm, kev txwv tsis pub xanthine oxidase ua rau kev nce hypoxanthine thiab xanthine. Thaum xanthine tsis tuaj yeem hloov mus rau purine ribotides, hypoxanthine tuaj yeem cawm mus rau purine ribotides adenosine thiab guanosine monophosphates. Ua kom nce siab ntawm cov ribotides no tuaj yeem ua rau cov kev tawm tswv yim inhibition ntawm amidophosphoribosyl transferase, thawj thiab tus nqi-txiav txim siab enzyme ntawm purine biosynthesis. Allopurinol, yog li ntawd, txo uric acid tsim thiab kuj tseem tuaj yeem ua kom tsis hnov ​​mob purine synthesis.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam hauv qab patent yog muab rau R & D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: allopurinol cas 315-30-0, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

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