3-Bromo-5-aminobenzotrifluoride CAS 54962-75-3

Khoom Qhia:

Cov Khoom Npe: 3-Bromo-5-aminobenzotrifluoride CAS TSIS: 54962-75-3

Txhais:

BenzenaMine, 3-broMo-5- (trifluoroMethyl) -;

3-Bromo-5- (trifluoromethyl) aniline, 5-Bromo-alpha, alpha, alpha-trifluoro-m-toluidine;

3-AMino-5-broMobenzotrifluoride [3-BroMo-5- (trifluoroMethyl) aniline];

Tshuaj& Cov Khoom Uas Lub Cev:

Zog: Cov kua ntshiab tsis muaj kob

Ntsuas: ≥98.0%

Qhov ceev: 1.697

Lub Ntsiab Lus Boiling: 220-223 ℃

Flash Point:> 110 ℃

Qhov Taw Qhia Refractive: 1.528

Cov Ntaub Ntawv Kev Nyab Xeeb:

WGK Lub Teb Chaws Yelemees: 3

Kos Npe: Lo Lus Ceeb Toom

Cov Lus Qhia Kev Nyab Xeeb: S26-S36

Cov Lus Ceeb Toom Yuav Muaj: R36 / 37/38

HS Code: 2921420090

Cov Cim Txog Kev Nyab Xeeb: Xi

Cov Nqe Lus Ceeb Toom: H315-H319-H335

Cov ntawv ceeb toom ua ntej: P261-P305 + P351 + P338

3-amino-5-bromotrifluorotoluene yog ib qho nruab nrab rau nilotinib, xaiv tyrosine kinase inhibitor uas tsom rau BCR-ABL kinase, C-KIT, thiab platelet-derived kev loj hlob yam receptor (PDGFR); Nws tsis muaj phiaj xwm tiv thaiv SRC tsev neeg. Nillotinib inhibits qhov loj hlob ntawm leukemia cell kab sib kho los ntawm BCR-ABL los ntawm khi rau ATP-khi qhov chaw ntawm BCR-ABL thiab inhibiting tyrosine kinase kev ua ub no, qhia kev ua haujlwm ntawm anti-imatinib-resistant BCR-ABL kinase hloov pauv. Nillotinib yog siv rau kev kho tus mob tshiab Philadelphia chromosomal positive (PH +) mob myelogenous leukemia (CML) hauv cov menyuam yaus thiab cov laus hnub nyoog 1 xyoos lossis laus dua. Kev Kho Mob Ntev thiab nrawm rau Philadelphia cov neeg laus nrog chromosomal zoo CML uas tiv thaiv lossis thev tsis tau rau kev kho ua ntej, suav nrog imatinib. Cov menyuam yaus uas muaj Philadelphia zoo CML rau ≥1 xyoo tau tiv taus lossis thev tsis raug rau yav dhau los tyrosine kinase inhibitor kho. Philadelphia yog chromosomal zoo (pH +) mob qog ua kom mob ntshav siab (txhua). Lub plab zom mov stromal qog (GIST) (refractory).

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Cim npe nrov: 3-bromo-5-aminobenzotrifluoride cas 54962-75-3, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

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