Yav tom ntej ntawm Lantern cov tshuaj tshiab tuaj yeem cia siab!

Tsis ntev los no, Lantern Pharma tshaj tawm cov ntaub ntawv ua ntej kawg ntawm cov tshuaj tshiab" LP-184" tsim los koom tes nrog Pancreatic Cancer Institute ntawm Fox Chase Cancer Center. Cov txiaj ntsig tshawb fawb pom tias cov tshuaj tuaj yeem txo cov qog nqaij hlav pancreatic ntau dua 90% hauv 8 lub lis piam!

Kab mob qog noj ntshav yog ib qho ntawm cov qog ua rau lub plab zom zaub mov, thiab paub tias yog&"huab tais mob qog noj ntshav &"; hauv thaj tsam ntawm cov qog. Cov ntaub ntawv kho mob qhia pom tias tus nqi kuaj mob thaum ntxov ntawm tus mob qog noj ntshav tsuas yog 5%, thiab 5-xyoo kev muaj sia nyob tseem tsawg dua 10%. Nws yog ib qho ntawm qhov phem tshaj plaws ua rau mob qog noj ntshav.

Txawm hais tias muaj ntau yam tsis xav tau hauv kev kho mob qog noj ntshav pancreatic, tus nqi ntawm kev phais phais tawm tsawg, thiab kev muaj sia nyob tom qab phais phais phais tsis zoo, mob qog noj ntshav tsis yog&"kab lus tuag." Nyob rau xyoo tsis ntev los no, kev kho lub hom phiaj thiab kev kho tshuaj tiv thaiv kab mob tau dhau los ua neeg nyiam, txhim kho kev kho mob zoo ntawm ntau cov qog nqaij tawv.

Ntawm lawv, cov neeg sawv cev tshaj plaws tsom rau tshuaj&& quot; Olapali&& quot; tau tshaj tawm xov xwm zoo. Qhov kev tshawb fawb zaum kawg ntawm" POLO", thawj txoj kev tshawb fawb raws li biomarkers los ntsuas PARA inhibitor olaparib, qhia tias olaparib nyob hauv qhov kev vam meej me me-tsis muaj txoj sia nyob yuav luag ob npaug! Pawg tswj hwm yog 3.8 lub hlis, thaum pab pawg olaparib tau mus txog 7.4 lub hlis, uas qhia tau tias olaparib muaj qhov cuam tshuam loj rau mob qog noj ntshav pancreatic.

Txawm li cas los xij, txhawm rau kov yeej" tus huab tais mob cancer" sai li sai tau, cov kws tshawb fawb kho mob thoob ntiaj teb tseem tab tom tshawb nrhiav ntau yam kev xaiv kho mob. Ntawm lawv, kev kho mob qog noj ntshav rau qee qhov tsis xws luag ntawm cov piam thaj tshwm sim los ntawm kev hloov pauv ntawm cov qog cell tau maj mam dhau los ua qhov tseem ceeb ntawm ntau yam tshuaj tiv thaiv kab mob qog noj ntshav.

AI lub tuam txhab kws tshuaj Lantern yog ib tus tswv cuab ntawm kev txhim kho DNA kev puas tsuaj. Lub tuam txhab tsis tsuas yog siv txoj kev kho rau kev tshawb fawb thiab kev txhim kho tshuaj oncology, tab sis kuj tseem siv cov txuj ci thev naus laus zis thev naus laus zis rau kev tshawb fawb tshuaj thiab kev txhim kho, uas zoo heev txhim kho kev sib piv ntawm cov tshuaj nrog cov neeg mob qog noj ntshav. Txhawm rau txo lub voj voog thiab tus nqi ntawm kev tshawb fawb tshuaj tshiab thiab kev txhim kho hauv kev kho mob theem 2, nws cov khoom LP-184, ua DNA tus neeg sawv cev alkylating, rov tshwm sim thaum kaj ntug ntawm huab tais tus mob qog noj ntshav" mob qog noj ntshav pancreatic" yog!

Cov txiaj ntsig ntsuas tau pom tias hauv cov qog nqaij hlav qog noj ntshav ua qauv xenograft nas, LP-184 tau ua kom sai thiab txo cov qog nqaij hlav pancreatic ntau dua 90% hauv 8 lub lis piam, thaum cov nas tsis kho tau nce cov qog nqaij hlav hauv 8 lub lis piam. Sijhawm ntxiv.

Tsis tsuas yog qhov ntawd, tom qab tau txais kev kho mob LP-184 rau 8 lub lis piam, 1 ntawm 4 tus nas muaj cov qog tau ploj mus, thiab qhov nruab nrab qhov seem me me ntawm 3 nas yog kwv yees li 7% ntawm cov qog qub, thiab nws yog 146 me dua li cov qog tsis kho . Sijhawm! Nws tau tshaj tawm tias Lantern npaj yuav pib ua daim ntawv thov IND nyob rau ib nrab xyoo ntawm lub xyoo no los txhawb nqa theem I kev sim tshuaj.

Yav tom ntej, nws cia siab tias kev kho mob qog noj ntshav tuaj yeem ua tiav qhov kev ua tiav loj thiab nrhiav cov cuab yeej ntse rau qhov tseem ceeb ntawm&"pancreas &"; kab kom sai li sai tau!