Neuron: yin - yaj sab ntawm dopamine

Rau xyoo lawm, cov kws saib xyuas kev puas siab ntseeg tau ntseeg tias cov neurotransmitter dopamine yog ob lub sijhawm - ntaj nqa tawm: tso rau hauv lub hlwb, ua khoom plig, cob qhia peb kom nrhiav kev lom zem, tab sis kuj muaj kev nrhiav tas li ntawm & quot; tshuaj & quot; ; uas ua rau muaj yees.

According to a new study from the University of California, Berkeley, this is just the dopamine side. On the other hand, dopamine is also released in response to unpleasant experiences, such as touching a hot teapot, which may be training the brain to avoid using them in the future. Related results were published in the recent & quot;Neuron & quot; magazine.

(Tau qhov twg los: Christine Liu duab)

Qhov tsis zoo ntawm dopamine tuaj yeem muaj kev cuam tshuam ntawm kev kho mob kev quav tshuaj thiab lwm yam kev puas siab puas ntsws. Piv txwv li, hauv cov kab mob xws li schizophrenia, qib dopamine hauv ntau qhov chaw ntawm lub hlwb ua qhov txawv txav, tej zaum vim yog qhov tsis txaus ntawm cov nqi zog thiab kev zam ntawm cov roj ntsha hauv lub hlwb. Kev muaj yees kuj yog los ntawm qhov lus teb uas tsis suav nrog kev lom zem thiab kev mob.

Stephan Lammel, tus pab xibfwb thiab cov laus tshaj lij cov xov tooj thev naus laus zis nyob hauv University of California, Berkeley tau hais tias: & quot; Qee tus neeg yuav tsuas saib rau qhov nqi zog tom ntej, thiab lawv yuav muaj kev pheej hmoo txaus siab txais kev pheej hmoo ntawm kev siv yeeb tshuaj Cov. Peb ua kom & # 39; t paub txog kev quav rau lub sijhawm no. Lub hauv paus neurobiological ntawm qee qhov siab txog - tus cwj pwm pheej hmoo ntawm cov tib neeg, xws li sib faib cuab yeej siv yeeb tshuaj, txawm hais tias kev tuag thiab kev mob ntsig txog nws tau lees paub. Nkag siab txog cov tshuaj hloov cov neural circuits koom tes ua li cas yuav muaj qhov tsis zoo nyob rau hauv lub ntsej muag ntawm nrhiav cov tshuaj Qhov cuam tshuam tseem ceeb ntawm kev pheej ua hauv tus cwj pwm. & quot;

Txawm hais tias qee tus neuroscientists tau ntev kwv yees txog lub peev xwm lub luag haujlwm ntawm dopamine nyob rau hauv lub cim ntawm aversion cov xwm txheej, nws cov cwm pwm ob lub cev tseem tau muab zais kom txog thaum tsis ntev los no, vim hais tias neurons uas tso dopamine nyob rau hauv kev teb rau cov khoom plig hauv lub hlwb tau muab tso rau hauv subcircuits uas txawv ntawm neurons uas tso dopamine. in. Teb rau qhov txhawb nqa qias neeg.

Thawj tus kws sau txog txoj kev tshawb no, Johannes de Jong, tuaj yeem sau ob dopamine subcircuits nyob rau tib lub sijhawm los ntawm kev cog cov kaus poom fiber ntau hauv ob cheeb tsam paj hlwb, uas tsuas yog ob peb millimeters sib nrug - siv cov txheej txheem tshiab hu ua fiber ntau kev thaij duab.

& quot;Our work describes for the first time a precise brain circuit in which the results of rewards and aversion are learned, & quot; Ramel said. & quot;There are separate neurons in our brain that are associated with appetite and aversion behaviors, which may explain why we are fighting for greater rewards while minimizing threats and dangers. This balanced behavior of approaching and avoiding learning It will definitely help the environment change in constant competition. & quot;

The newly discovered dopamine effect and more and more people realize that neurotransmitters have different roles in different areas of the brain, such as their function in voluntary exercise, which is affected in Parkinson & #39;s disease. The results also explained the earlier conflicting experiments, some of which showed an increased response of dopamine to aversive stimuli, while others did not.

& quot;We no longer consider dopamine neurons as a homogenous cell population in the brain. It modulates reward and happiness to a clearer and more detailed picture of the effects of dopamine, depending on where it is released in the brain, & quot; Lamel said. . (Bioon.com)

qhov chaw: Johannes W. de Jong li al, & nbsp;A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System, & nbsp;Neuron & nbsp;(2018). DOI: 10.1016 / j.neuron.2018.11. 005 0010010 nbsp;