-Nicotinamide Mononucleotide NMN CAS 1094-61-7

Khoom Qhia:

Cov Khoom Khoom Npe: β-Nicotinamide Mononucleotide NMN CAS TSIS TAU: 1094-61-7

Txhais:

Beta-Nicotinamide ribose monophosphate;

Nicotinamide ribonucleoside 5' -phosphate;

3-Carbamoyl-1- [5-O- (hydroxyphosphinato) -β-D-ribofuranosyl] pyridinium;

3- (Aminocarbonyl) -1- (5-O-phosphono-bD-ribofuranosyl) pyridinium Hydroxide Sab Hauv ntsev;

[(2R, 3S, 4R, 5R) -5- (3-Carbamoyl-1-pyridiniumyl) -3,4-dihydroxytetrahydro-2-furanyl] methyl hydrogen phosphate;

Tshuaj& Lub cev nqaij daim tawv

Zog: Cov hmoov dawb dawb.

Ntsuas: ≥99.0%

Melting point: ＞ 96 ℃

PSA: 176.06000

LogP: -1.06000

Solubility: Solubility: Methanol (Me ntsis), Dej (Me ntsis).

Kev Ruaj Ntseg: Heev Hygroscopic

Qeb: Nicotine Derivatives; Nucleotides; Tshuaj / API Tshuaj Tsis Txaus / Cov Metabolites;

Cov Ntaub Ntawv Kev Nyab Xeeb:

HS Code: 2934999099

Cov Khoom Siv Tiv Thaiv Tus Kheej: Pob muag; Hnab looj tes; hom N95 (Asmeskas); hom P1 (EN143) lub tshuab pa ntsuas pa.

RIDADR: NONH rau txhua hom kev thauj khoom

WGK Lub Teb Chaws Yelemees: 3

Cia：Muab cia rau hauv qhov chaw txias thiab qhuav zoo kaw lub thawv. Cia kom deb ntawm ya raws thiab muaj zog lub teeb / cua sov.

Daim ntawv thov:

1. β-nicotinamide mononucleotide yog ib nrab nyob hauvNAD +biosynthesis ua los ntawm nicotinamide (NAM) thiab phosphoribosyl pyrophosphate (PRPP) los ntawm nicotinamide phosphoribosyl transferase enzyme.

2. NMN yog cov khoom lag luam ntawm cov sib ntxiv ntawm Nicotinamide phosphoribosyltransferase (eNAMPT) kev cuam tshuam thiab qhov tseem ceeb NAD + nruab nrab. Nws ameliorates qabzib tsis kam txais los ntawm kev rov qab NAD + qib hauv HFD-hob T2D cov nas. Nws tseem txhim kho qhov mob hepatic insulin rhiab thiab rov qab tso cov noob qhia ntsig txog oxidative kev nyuaj siab, kev teb, thiab lub suab circadian, ib nrab los ntawm SIRT1 ua kom.

3. Nicotinamide mononucleotide (GG quot; NMN" thiab" β-NMN") yog nucleotide muab tau los ntawm ribose thiab nicotinamide. Niacinamide (nicotinamide,) yog ib hom tshuaj vitamin B3 (niacin.) Ua lub tshuaj biochemical tus npau suav ntawm NAD +, nws yuav muaj txiaj ntsig zoo rau kev tiv thaiv pellagra.

Nws daim ntawv tsis meej, niacin, pom muaj ntau yam khoom noj muaj txiaj ntsig: Txiv laum huab xeeb, Cov nceb (portobello, grilled), Avocados, Ntsuab Peas (tshiab), thiab qee yam ntses thiab tsiaj nqaij.

Hauv cov kev tshawb fawb [ntawm nas], NMN tau pom tias ua kom rov muaj hnub nyoog ntsig txog txoj kev cuam tshuam ntawm txoj hlab ntsha los ntawm kev txo qis oxidative kev ntxhov siab.

Lub zog tiv thaiv kev laus yuav raug tshuaj ntsuam rau tib neeg thaum Lub Xya Hli 2016.

4. The -nicotinamide mononucleotide (NMN) tau siv los kawm txog cov lus qhia txog RNA aptamers thiab cov txheej txheem ua kom tsis muaj teeb meem uas muaj nicotinamide mononucleotide (mn-nmn) -activated RNA fragment.

5. beta-Nicotinamide mononucleotide (β-NMN), Ntsiab NAD + nruab nrab.

Peb lub Hoobkas tsim tawm Beta-NMN, tshuab paub tab, cov khoom lag luam ruaj khov, cov khoom ua tiav zoo.

Cov Ntaub Ntawv Nres: Muaj Hauv Tshuag.

Peb tuaj yeem muab β-D-NMN COA (daim ntawv pov thawj ntawm kev tsom xam), Nicotinamide-1-Ium-1-Beta-D-Ribofuranoside5' -Phosphate MOA (Txoj Kev Ntsuam Xyuas), Nicotinamide D-ribonucleotide ROS (Txoj kev ntawm kev coj los ua ke ), beta-Nicotinamide ribonucleotide MSDS (Cov Khoom Siv Kev Nyab Xeeb Cov Ntaub Ntawv) thiab lwm yam kev txhawb nqa rau koj!

Nicotinamide mononucleotide ua si lub luag haujlwm tseem ceeb hauv kev tsim hluav taws xob hauv tib neeg lub hlwb. Nws tau koom nrog hauv kev coj ua ke ntawm intracellular NAD (nicotinamide adenine dinucleotide, ib qho tseem ceeb coenzyme ntawm hloov lub zog ntawm tes).

Nicotinamide mononucleotide yuav hloov pauv mus rau hauv nicotinamide adenine dinucleotide (NAD), uas yog qhov tseem ceeb rau lub zog metabolism hauv vivo. Hauv kev sim tshuaj nas, nws tau tshaj tawm tias nicotinamide mononucleotide tuaj yeem ua kom muaj lub noob hu ua acetylase hauv vivo, yog li ua kom ntev lub neej thiab kho ntshav qab zib. NAD yog tshuaj uas tsim los ntawm tib neeg lub cev. Kev tshawb nrhiav pom tias cov ntsiab lus ntawm NAD hauv tib neeg lub cev yuav txo qis nrog kev nce hnub nyoog.

Nicotinamide ribotide (NMN) yog qhov tseem ceeb intermediate metabolite hauv nicotinate thiab nicotinamide metabolism hauv kev. Cov nas tsiaj siv feem ntau siv cov nicotinamide ntau dua li cov nicotinic acid ua qhov ua ntej rau NAD biosynthesis. Hloov chaw rau deamidation rau nicotinic acid, nicotinamide hloov ncaj qha rau NMN los ntawm nicotinamide phosphoribosyltransferase (NAMPT, EC 2. 4. 2. 12). Lub zog nemotinamide mononucleotide adenylyltransferase (NMNAT, EC 2. 7. 7. 1), uas yog tus tswv cuab ntawm nucleotidyltransferase alpha / beta-phosphodiesterase superfamily, catalyzes cov tshuaj tiv thaiv NMN + ATP<=gg gt;="" nicotinamide="" adenine="" dinucleotide="" (nad)="" +="" ppi,="" sawv="" cev="" rau="" theem="" kawg="" ntawm="" biosynthesis="" ntawm="" nad.="" nad="" yog="" ib="" qho="" qauv="" (molecule)="" uas="" ua="" lub="" luag="" haujlwm="" tseem="" ceeb="" ua="" tus="" cofactor="" hauv="" cov="" xovtooj="" ntawm="" kev="" rov="" ua="" lub="" cev.="" yog="" li="" nmn="" yog="" qhov="" tseem="" ceeb="" metabolite="" rau="" kev="" saib="" xyuas="" ntawm="" nad="" biosynthesis="" ib="" txwm.="" circulating="" nmn="" qib="" yuav="" ua="" lub="" luag="" haujlwm="" tseem="" ceeb="" hauv="" kev="" tswj="" hwm="" kev="" ua="" haujlwm="" ntawm="" tes="" hauv="" kev="" ua="" haujlwm="" hauv="" physiological="" thiab="">

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: nic-nicotinamide mononucleotide nmn cas 1094-61-7, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

• Tug: Β-Nicotinamide Adenine Dinucleotide Disodium Ntsev NADH CAS 606-68-8
• Tom ntej: Β-Nicotinamide Adenine Dinucleotide NAD CAS 53-84-9