Tolvaptan CAS 150683-30-0

Khoom Piav Qhia:

Khoom Lub Npe: Tolvaptan CAS TSIS TAU: 150683-30-0

Lub ntsiab lus:

Tolvaptan;

Samsca;

benzazepine derivative, 32;

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Dawb rau ziab hmoov

Kev Ntsuas: ≥99.00%

Ceev: 1.311 ± 0.06 g/cm3 (Kwv yees)

Melting Point: 219-222 ℃

Kub Point: 594.4 ± 50.0 ℃ (Kwv yees)

Cia Temp.: Tub yees

Solubility: DMSO: ≥15mg/ml

Pka: 13.00 ± 0.70 (Kwv yees)

Vapor Siab: 0.0 ± 1.8 mmHg ntawm 25 ℃

Index ntawm Refraction: 1.664

Cov Ntaub Ntawv Kev Nyab Xeeb:

WGK Lub Tebchaws Yelemees: 3

Tolvaptan (cov npe lag luam Samsca thiab Jinarc) yog qhov ncauj xaiv vasopressin antagonist tsim los ntawm Otsuka rau kev kho mob hyponatremia, thiab nws yog cov tsis peptide xaiv antidiuretic hormone receptor antagonist. Cov tshuaj tuaj yeem ua rau kom muaj cov tshuaj sodium ions ntau ntxiv hauv cov ntshav, thiab pab kom cov dej ntau dhau los ntawm cov zis. Cov tshuaj tuaj yeem txhim kho lub peev xwm ntawm lub raum los daws cov dej, thiab txo qis qhov hnyav thiab ua rau cov neeg mob thaum tsis koom nrog kev tso tawm cov kua dej ntau ntxiv, tsis muaj kev puas tsuaj cov ntshav electrolyte tshuav. Cov tshuaj tuaj yeem siv los kho tus mob hyponatremia tshwm sim los ntawm lub plawv tsis ua haujlwm, ntau yam kab mob edematous, mob ntshav siab thiab antidiuretic hormone deficiency syndrome. Txoj kev tshawb nrhiav pom tias, thaum cov ntshav sodium concentration qis, txhawm rau tswj hwm qhov sib npaug ntawm sodium concentration sab hauv thiab sab nraud ntawm tes, cov kua dej sab nraud yuav nkag rau hauv lub cell, yog li cov cell yuav o tuaj. Thaum lub hlwb hlwb swell, nws yuav ua rau muaj ntau yam tsos mob ntawm hyponatremia, suav nrog kiv taub hau, qaug zog, mob taub hau, xeev siab, tsis meej pem, nco qab thiab ntuav. Kev mob hyponatremia hnyav tuaj yeem ua rau coma thiab tuag. Tsis muaj kev kawm sib xws ntawm tolvaptan ntsiav tshuaj hauv cov neeg mob uas muaj mob hyponatremia hnyav.

Nws yog qhov kev xaiv, sib tw arginine vasopressin V2 receptor antagonist siv los kho hyponatremia (qib ntshav qis sodium) cuam tshuam nrog kev mob plawv tsis ua haujlwm, mob ntshav qab zib, thiab cov tsos mob ntawm cov tshuaj tsis haum tshuaj tiv thaiv kab mob (SIADH).

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: tolvaptan cas 150683-30-0, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

• Tug: 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO [B] AZEPIN-5-ONE CAS 160129-45-3
• Tom ntej: 2-bromo-4'-chloro-2 '-(o-fluorobenzoyl) acetanilide CAS 1584-62-9