Hu rau:Errol Zhou (Mr.)
Tel: ntxiv 86-551-65523315
Mobile/WhatsApp: ntxiv 86 17705606359
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Skype:lucytoday@hotmail.com
Email:sales@homesunshinepharma.com
Ntxiv:1002, Huanmao Tsev, No.105, Mengcheng Txoj kev, Hefei Lub zos, 230061 Tuam Tshoj
CAS TSIS TAU: 1100598-32-0
Cov Qauv Nqaij: C29H28N6O2
Cov Nqa Molecular: 492.57200
EINECS TSIS MUAJ: NA
MDL TSIS TAU: MFCD18452823
Khoom Qhia:
Khoom npe: tepotinib CAS TSIS: 1100598-32-0
Txhais:
3- (1- (3- (5- (1-methylpiperidin-4-ylmethoxy) pyrimidin-2-yl) benzyl) -1,6-dihydro-6-oxopyridazin-3-yl) benzonitrile;
EMD 1214063;
Tshuaj& Cov Khoom Uas Lub Cev:
Tsos: Off-dawb rau daj ntseg beige
Ntsuas: ≥99.0%
Qhov ceev: 1.25
Flash Point: 332.7 ± 34.3 ℃
Lub Ntsiab Kub: 626.5 ± 65.0 ℃ (Xav Tau)
Vapor Siab: 0.0 ± 1.8 mmHg ntawm 25 ℃
Qhov ntsuas ntawm kwv yees: 1.660
Tepotinib yog qhov muaj kev tiv thaiv siab tiv thaiv MET. Hauv cov qauv xenograft, tau txais kev tiv taus ntawm EGFR TKIs ntawm EGFR T790 M hloov pauv tuaj yeem kov yeej nrog kev kho tepotinib. EMD 1214063 yog qhov muaj zog thiab xaiv c-Met inhibitor nrog IC50 ntawm 4 nM,> 200-quav xaiv rau c-Met tshaj IRAK4, TrkA, Axl, IRAK1, thiab Mer. Tus nqi IC50: 4 nM [1] Lub Hom Phiaj: c-Metin vitro: EMD 1214063 tiv thaiv HGF-hob c-Met phosphorylation hauv A549 hlwb nrog IC50 ntawm 6 nM.
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.
Cim npe nrov: tepotinib cas 1100598-32-0, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag
