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Ntxiv:1002, Huanmao Tsev, No.105, Mengcheng Txoj kev, Hefei Lub zos, 230061 Tuam Tshoj
CAS TSIS TAU: 143900-44-1
Cov Qauv Sib Nqus: C10H19TSIS MUAJ3
Cov Nqa Molecular: 201.26
EINECS TSIS MUAJ: 626-373-5
MDL TSIS TAU: MFCD04115307 / MFCD06659041
Khoom Qhia:
Khoom Siv Lub Npe: (S) -1-Boc-3-hydroxypiperidine CAS TSIS: 143900-44-1
Txhais:
(S) -1-Tert-Butoxycarbonyl-3-Hydroxypiperidine;
(S) -3-Hydroxy-Piperidine-1-Carboxylicacidtert-Butylester;
(S) -3-Hydroxy-1- (Tert-Butoxycarbonyl) Piperidine;
(S) -1-Boc-3-Piperidinol;
(S) -N- (Tert-Butoxycarbonyl) -3-Hydroxypiperidinehydrochloride;
(S) -N-Boc-3-Hydroxypiperidine;
(S) -Tertbutyl-3-Hydroxypiperidine-1-Carboxylate;
(S) -1- (tert-Butoxycarbonyl) -3-hydroxypiperidine;
Tshuaj& Cov Khoom Uas Lub Cev:
Zog: Dawb rau daj hmoov.
Ntsuas: ≥99.0%
Qhov ceev: 1.107g / cm3
Melting point: 34-40 ℃
Lub Ntsiab Kub: 292.3 ℃ ntawm 760 mmHg
Flash Point: 110 ℃
Nqe Taw Qhia Tshwj Xeeb: 1.495
Vapor Siab: 0.0mmHg ntawm 25 ° C
PSA: 49.77000
LogP: 1.31610
Pka: 14.74 ± 0.30 (Teem Tau)
Solubility: Soluble hauv methanol.
Qeb: Piperidines; Piperazine; Kws Tshuaj / API Tshuaj Tshuaj Nruab Nrab;
Cov Ntaub Ntawv Kev Nyab Xeeb:
HS Code: 2933399090
Kev Nyab Xeeb Kev Nyab Xeeb: S26
Cov Lus Ceeb Toom Yuav Muaj: R36 / 37/38
Cov Cim Txog Kev Nyab Xeeb: Xi
Cia：Muab cia rau hauv qhov chaw txias thiab qhuav zoo kaw lub thawv. Cia kom deb ntawm ya raws thiab muaj zog lub teeb / cua sov.
Daim ntawv thov:
1,1-dimethylethyl (3S) -3-hydroxypiperidine-1-carboxylate yog qhov tseem ceeb chiral intermediate rau cov hluavtaws ntawm ibrutinib, ib qho tshuaj anticancer tsom B-cell malignancies. Synthesis ntawm cov tshuaj intermediates suav nrog ibrutinib, API ntawm cov tshuaj tshiab khiv Imbruvica, rau kev kho mob ntawm cov qog ntshav.
Peb lub Hoobkas tsim khoom siv (3S) -1- (tert-Butyloxycarbonyl) piperidine-3-ol, paub tab thev naus laus zis, cov zis zoo, ruaj khov.
Cov Ntaub Ntawv Nres: Muaj Hauv Tshuag.
Peb tuaj yeem muab (S) -3-hydroxy-N-Boc-piperidine COA (daim ntawv pov thawj ntawm kev tsom xam), (S) -1-BOC-Piperidin-3-olMOA (Txoj Kev Ntsuam Xyuas), (3S) -1- (tert -Butoxycarbonyl) -3-hydroxypiperidine ROS (Qhov tseem ceeb ntawm cov khoom siv), (S) -N-tert-Butoxycarbonyl-3-hydroxypiperidine MSDS (Cov Khoom Siv Kev Nyab Xeeb Cov Ntaub Ntawv) thiab lwm yam kev txhawb nqa rau koj!
peb tuaj yeem muabIbrutinib Thiab Intermediates:
Ibrutinib Thiab Intermediates | TSIS MUAJ |
Ibrutinib | |
1-Piperidinecarboxylicacid, 3- [4-amino-3- (4-phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-1-yl] -, 1,1-dimethylethylester, (3R) - | |
(S) -1-Boc-3-hydroxypiperidine | |
3- (4-Phenoxy-phenyl) -1-piperidin-3-yl-1H-pyrazolo [3,4-d] pyrimidin-4-ylamine | |
5- (4-phenoxyphenyl) -7H-pyrrolo [2,3-d] pyrimidin-4-ylamine | |
5-amino-3- (4-phenoxyphenyl) -1H-pyrazole-4-carbonitrile | |
(R) -3- (4-phenoxyphenyl) -1- (piperidin-3-yl) -1H-pyrazolo [3,4-d] pyrimidin-4-aminedihydrochloride | |
4-Amino-3-iodo-1H-pyrazolo [3,4-d] pyrimidine | |
4-Phenoxyphenyl boronic acid |
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.
Cim npe nrov: (s) -1-boc-3-hydroxypiperidine cas tsis muaj 143900-44-1, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag
![(1S, 3S, 5S) -3- (Aminocarbonyl) -2-azabicyclo [3.1.0] hexane-2-carboxylic Acid Tert-butyl Ester CAS 361440-67-7](/uploads/201922606/small/-1s-3s-5s-3-aminocarbonyl-2-azabicyclo-3-1-036317964323.png?size=264x0)
![1-Piperidinecarboxylicacid, 3- [4-amino-3- (4-phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-1-yl] -, 1,1-dimethylethylester, (3R) - CAS TSIS MUAJ 1022150 -11-3](/uploads/201922606/small/1-piperidinecarboxylicacid-3-4-amino-3-453419036422.jpg?size=264x0)
