Repaglinide CAS 135062-02-1

Khoom Piav Qhia:

Khoom Lub Npe: Repaglinide CAS TSIS TAU: 135062-02-1

Lub ntsiab lus:

(S) -2-Ethoxy-4- (2-((3-methyl-1- (2- (piperidin-1-yl) phenyl) butyl) amino) -2-oxoethyl) benzoic acid;

Prandin, GlucoNorm, NovoNorm;

2-Ethoxy-4- [2-[(1S) -3-Methyl-1- [2- (1-Piperidinyl) Phenyl] Butyl] Amino] -2-Oxoethyl] Benzoic Acid;

Tshuaj& Lub Cev Muaj Zog:

Tsos: Dawb rau dawb-dawb khoom

Kev Ntsuas: ≥99.00%

Ceev: 1.137g/cm3

Kub Point: 672.9 ℃ ntawm 760 mmHg

Melting Point: 129-130 ℃

Flash Point: 360.8 ℃

Refractive Index: 1.567

Cia Li Cas: 2-8 ℃

Vapor Siab: 5E-19mmHg ntawm 25 ℃

Cov Ntaub Ntawv Kev Nyab Xeeb:

PIB: 000000033825

HS Code: 2933399090

WGK Lub Tebchaws Yelemees: 2

Repaglinide yog tshuaj tiv thaiv kab mob ntshav qab zib hauv chav kawm ntawm cov tshuaj hu ua meglitinides, thiab tau tsim tawm xyoo 1983. Repaglinide yog tshuaj noj qhov ncauj siv ntxiv rau kev noj zaub mov thiab ua kom tswj ntshav qab zib hauv hom 2 mob ntshav qab zib mellitus. Cov txheej txheem ntawm kev ua ntawm repaglinide suav nrog txhawb kev tso tawm cov insulin los ntawm cells-islet cells ntawm cov txiav txiav; zoo li lwm yam tshuaj tiv thaiv kab mob ntshav qab zib, qhov cuam tshuam tseem ceeb cuam tshuam yog hypoglycemia. Nws tau muag los ntawm Novo Nordisk raws li lub npe Prandin hauv Asmeskas, GlucoNorm hauv Canada, Surepost hauv Nyij Pooj, Repaglinide hauv Egypt los ntawm EIPICO, thiab NovoNorm lwm qhov. Hauv Nyij Pooj nws tau tsim los ntawm Dainippon Sumitomo Pharma. Repaglinide (AG-EE 623ZW) yog carbamoylmethyl benzoic acid (CMBA) derivative, uas tsis ntev los no tau muaj rau kev kho mob ntshav qab zib hom II. IC50 tus nqi: Lub Hom Phiaj: Repaglinide tau nqus sai heev (tmax tsawg dua 1 teev) nrog t1/2 ntawm tsawg dua ib teev. Tsis tas li ntawd, repaglinide tsis ua haujlwm hauv lub siab thiab ntau dua 90 % tso tawm los ntawm cov kua tsib. Repaglinide (1 mg/kg po) tau ua haujlwm zoo (P< 0.001)="" raws="" li="" tus="" neeg="" tso="" tshuaj="" insulin="" tso="" tawm="" hauv="" tus="" qauv="" nas="" (koob="" tshuaj="" tsawg="" streptozotocin)="" ntawm="" hom="" 2="" mob="" ntshav="" qab="">

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: repaglinide cas 135062-02-1, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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