(R) -Rivaroxaban CAS {{1}}

Khoom Qhia:

Khoom npe: (R) -Rivaroxaban CAS TSIS: 865479-71-6

Txhais:

5-R-Rivaroxaban;

5-chloro-N - [[(5R) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] -1,3-oxazolidin-5-yl] methyl] thiophene-2-carboxamide ;

2-Thiophenecarboxamide, 5-chloro-N - [[(5R) -2-oxo-3- [4- (3-oxo-4-morpholinyl) phenyl] -5-oxazolidinyl] methyl] -;

Tshuaj& Cov Khoom Uas Lub Cev:

Zog: Cov hmoov dawb dawb

Ntsuas: ≥97.0%

Qhov ceev: 1.46g / cm3

Lub Ntsiab Kub: 732.6 ℃ ntawm 760 mmHg

Flash Point: 396.9 ℃

5-R-Rivaroxaban yog (R) -enantiomer ntawm Rivaroxaban. Rivaroxaban (BAY 59-7939) yog qhov muaj zog thiab xaiv ntau, ncaj qha Factor Xa (FXa) inhibitor, ua tiav lub zog muaj zog tiv thaiv FXa potency (IC50 0.7 nM; Ki 0.4 nM).

Rivaroxaban (BAY 59-7939) yog qhov ncauj, ncaj qha Factor Xa (FXa) inhibitor hauv kev txhim kho rau kev tiv thaiv thiab kev kho mob ntawm txoj hlab ntshav thiab txoj hlab ntshav. Rivaroxaban kev sib tw inhibits tib neeg FXa (Ki 0.4 nM) nrog> 10 000-fold ntau dua xaiv ntau dua li rau lwm cov kev pabcuam tiv thaiv kab mob; nws kuj inhibits prothrombinase kev ua haujlwm (IC50 2.1 nM). Rivaroxaban inhibits endogenous FXa muaj txiaj ntsig ntau hauv tib neeg thiab luav ntshav (IC50 21 nM) dua li cov ntshav plasma (IC50 290 nM). Nws qhia txog cov teebmeem anticoagulant hauv tib neeg plasma, ob zaug prothrombin lub sijhawm (PT) thiab ua kom lub sijhawm thromboplastin tsawg kawg ntawm 0.23 thiab 0.69 μM, feem.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov hu rau peb!

Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: (r) -rivaroxaban cas 865479-71-6, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

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