PZM21 CAS 1997387-43-5

Khoom Piav Qhia:

Khoom Lub Npe: PZM21 CAS TSIS TAU: 1997387-43-5

Lub ntsiab lus:

1-[(2S) -2- (Dimethylamino) -3- (4-hydroxyphenyl) propyl] -3-[(2S) -1- (thiophen-3-yl) propan-2-yl] urea;

1-[(2S) -2- (Dimethylamino) -3- (4-hydroxyphenyl) propyl] -3-[(2S) -1- (thiophen-3-yl) propan-2-yl] urea;

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Dawb rau dawb-dawb hmoov hmoov

Kev Ntsuas: ≥98.0%

Kub Point: 583.8 ± 50.0 ℃ (Kwv yees)

Ceev: 1.169 ± 0.06 g/cm3 (Kwv yees)

PKa: 10.06 ± 0.15 (kwv yees)

Dej Solubility: 10 mM hauv DMSO

PZM21 yog lub zog thiab xaiv -opioid receptor agonist nrog EC50 ntawm 1.8 nM. PZM21 yog tus xaiv -receptor agonist (EC50=4.6 nM). PZM21 tau tshaj tawm los ua pov thawj kev tsis ncaj ncees rau Gi txoj kev taw qhia txog kev raug ntes-3. Cov khoom nthuav tawm 500-quav xaiv rau μ dhau δ receptors thiab tsis muaj kev tshawb pom ntawm κ lossis nociceptin receptors thiab pawg ntawm 316 lwm GPCRs. PZM21 induces analgesia hauv nas ntsuas phaj kub, tab sis tsis yog kev ntsuas tus Tsov tus tw thiab nthuav tawm tsis muaj qhov xwm txheej tseem ceeb nyiam qhov lus teb hauv vivo kev ntsuas. CNS nkag mus.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: pzm21 cas 1997387-43-5, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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