PQR530 CAS 1927857-61-1

Khoom Piav Qhia:

Khoom Lub Npe: PQR530 CAS TSIS TAU: 1927857-61-1

Lub ntsiab lus:

4- (difluoromethyl) -5- [4-[(3S) -3-methylmorpholin-4-yl] -6-morpholin-4-yl-1,3,5-triazin-2-yl] pyridin-2-amine ;

(S) -4- (Difluoromethyl) -5- (4- (3-methylmorpholino) -6-morpholino-1,3,5-triazin-2-yl) pyridin-2-amine;

2-Pyridinamine, 4- (difluoromethyl) -5- [4-[(3S) -3-methyl-4-morpholinyl] -6- (4-morpholinyl) -1,3,5-triazin-2-yl]- ;

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Cov hmoov av

Kev Ntsuas: ≥98.0%

Ceev: 1.338 ± 0.06 g/cm3 (Kwv yees)

Kub Point: 660.7 ± 65.0 ℃ (Kwv yees)

PKa: 5.05 ± 0.10 (kwv yees)

Dej Solubility: Xyaum ua tsis tau (0.057 g/L) (25 ℃)

PQR530 yog lub zog yias ob lub lauj kaub PI3K/mTOR inhibitor tseem tab tom kuaj mob thib ob hauv xyoo 2016. Aberrant activation of the PI3K/mTOR signaling pathway txhawb kev loj hlob ntawm cov qog nqaij hlav qog nqaij hlav. Txoj kev tshawb no pom tias PQR530 txwv tsis pub txhua PI3K isoforms thiab cov hom phiaj ntawm cov tsiaj ntawm rapamycin (mTOR) complexes C1/2 muaj zog thiab xaiv tawm tsam kev mob qog noj ntshav.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: pqr530 cas 1927857-61-1, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

• Tug: CPD1563 CAS 2137975-08-5
• Tom ntej: Biphenyl-2-ylcarbamicacid1- (2-{[4- (4-carbamoylpiperidin-1-ylmethyl) benzoyl] methylamino} ethyl) piperidin-4-ylester CAS 864750-70-9