Hu rau:Errol Zhou (Mr.)
Tel: ntxiv 86-551-65523315
Mobile/WhatsApp: ntxiv 86 17705606359
QQ:196299583
Skype:lucytoday@hotmail.com
Email:sales@homesunshinepharma.com
Ntxiv:1002, Huanmao Tsev, No.105, Mengcheng Txoj kev, Hefei Lub zos, 230061 Tuam Tshoj
CAS TSIS TAU: 1092364-38-9
Cov mis mos molecular: C23H21Cl2FN4O3
Molecular phaus: 491.34200
EINECS NO: Tsis yog
MDL NO: NA
Khoom Piav Qhia:
Khoom Lub Npe: Poziotinib CAS TSIS TAU: 1092364-38-9
Lub ntsiab lus:
NOV120101;
UNII-OEI6OOU6IK;
1- [4- [4- (3,4-dichloro-2-fluoroanilino) -7-methoxyquinazolin-6-yl] oxypiperidin-1-yl] prop-2-en-1-ib;
Tshuaj& Lub Cev Muaj Zog:
Tshwm sim: Cov hmoov av
Kev Ntsuas: ≥99.0%
Ceev: 1.409 ± 0.06 g/cm3 (Kwv yees)
Cov Kub Kub: 629.7 ± 55.0 ℃ (Kwv yees)
PKa: 5.35 ± 0.30 (Kwv yees)
Flash Point: 334.6 ± 31.5 ℃
Vapor Siab: 0.0 ± 1.8 mmHg ntawm 25 ℃
Index ntawm Refraction: 1.645
Poziotinib [1. {4. [4. (3,4. Dichloro.2.monofluoroaniline) -7-methoxyquinazoline-6. Cov pa]. 1. Piperidinyl} propan-2-ene-1one (1)] yog cov tshuaj tua kab mob qog noj ntshav ntawm lub qhov ncauj tshiab tsim los ntawm Seoul Medical University hauv Kaus Lim Qab Teb xyoo 2008. Nws tau siv rau kev kho mob ntawm lub mis thiab mob qog noj ntshav, thiab muaj lub hom phiaj me me inhibitor ntawm tyrosine kinase. Tam sim no nws tseem nyob hauv Phase II / III kev tshawb fawb soj ntsuam thiab tuaj yeem siv ib leeg lossis ua ke rau kev kho mob ntawm lub plab, tsis mob qog noj ntshav ntawm tes thiab mob qog noj ntshav mis. Poziotinib tiv taus erlotinib thiab gefitinib EGFR L858R / T790M Ob lub hlwb hloov pauv muaj lub zog tiv thaiv kab mob.
Kev siv ua ke ntawm Poziotinib (HM781-36B) thiab 5-fluorouracil, platinum compound, paclitaxel lossis gemcitabine qhia tau tias muaj kev cuam tshuam zoo rau kev cuam tshuam ntawm kev tshaj tawm ntawm tib neeg epidermis No. 2 (HER2). Ib tiam tshiab thib peb tiv thaiv qog nqaij hlav cell inhibitor tom qab kinase inhibitor afatinib.
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.
Cim npe nrov: poziotinib cas 1092364-38-9, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag
