ORM-15341 CAS 1297537-33-7

Khoom Piav Qhia:

Khoom Lub Npe: ORM-15341 CAS TSIS TAU: 1297537-33-7

Lub ntsiab lus:

(S) -3-acetyl-N- (1- (3- (3-chloro-4-cyanophenyl) -1H-pyrazol-1-yl) propan-2-yl) -1H-pyrazole-5-carboxamide;

ORM-15341;

(S) -5-acetyl-N- (1- (3- (3-chloro-4-cyanophenyl) -1H-pyrazol-1-yl) propan-2-yl) -1H-pyrazole-3-carboxamide;

Tshuaj& Lub Cev Muaj Zog:

Tsos: Hmoov

Kev Ntsuas: ≥99.00%

Cov Kub Kub: 714.7 ± 60.0 ℃ (Kwv yees)

Ceev: 1.41 ± 0.1 g/cm3 (Kwv yees)

Pka: 8.70 ± 0.10 (kwv yees)

Solubility: DMSO: ＞ 37 mg/mL

Cia: -20 ℃ Khov

ORM-15341 yog lub zog muaj zog thiab muaj kev tawm tsam rau tib neeg AR (hAR) nrog IC50 qhov tseem ceeb ntawm 38 nM raws li qhia los ntawm kev hloov pauv kev sim hauv AR-HEK293 cov hlwb ruaj khov nthuav qhia ntev-hAR thiab androgen-responsive luciferase reporter gene gene construct.IC50 tus nqi: 38 nMTarget: androgen receptorin vitro: Hauv kev sib tw AR kev sib tw ntsuas, qhov txwv tsis pub tas li (Ki) qhov tseem ceeb ntawm ORM-15341 yog 8 nM. ORM-15341 ua lub luag haujlwm tiv thaiv tag nrho rau txhua qhov kev sim hloov pauv ARs, nrog IC50 ntawm 25, 51, 700, thiab 1160 nM rau wtAR, AR (F876L), AR (T877A), thiab AR (W741L).

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: orm-15341 cas 1297537-33-7, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

• Tug: 2-Amino-5-chloro-2'-fluorobenzophenone CAS 784-38-3
• Tom ntej: 5-ACETYL-1H-PYRAZOLE-3-CARBOXYLIC ACID CAS 1297537-45-1