Olaparib CAS 763113-22-0

Khoom Piav Qhia

Cov Khoom Npe: Olaparib CAS TSIS TAU: 763113-22-0

0010010 nbsp;

0010010 nbsp;

Txhais:

1 (2 H) -Phthalazinone, 4 - [[3 - [[4- (cyclopropylcarbonyl) - 1 - piperazinyl] carbonyl] -4-fluorophenyl] methyl] -;

1- (Cyclopropylcarbonyl) -4- [5 - [(3, 4-dihydro-4-oxo-1-phthalazinyl) methyl] -2-fluorobenzoyl] piperazine;

AZD - 2281; AZD 2281;

azd 2281 Olaparib;

4- (3 - {[4- (Cyclopropylcarbonyl) -1-piperazinyl] carbonyl} -4-fluorobenzyl) -1 (2 H) -phthalazinone;

Olaparib; Lynparza;

4- (3 - {[4- (Cyclopropylcarbonyl) piperazin-1-yl] carbonyl} -4-fluorobenzyl) phthalazin-1 (2 H) -one;

0010010 nbsp;

0010010 nbsp;

Tshuaj Txhaum 0010010 amp; Lub cev nqaij daim tawv

Zog: dawb Khoom.

Ntsuas: ≥ 99. 5%

Ntom: 1. 43 g / cm 3

0010010 nbsp;

0010010 nbsp;

Olaparib (AZD-2281, lub npe lag luam Lynparza) yog FDA pom zoo rau kev kho mob rau mob qog noj ntshav, tsim los ntawm KuDOS Pharmaceuticals thiab tom qab ntawd los ntawm AstraZeneca. Nws yog PARP inhibitor, inhibiting poly ADP ribose polymerase (PARP), ib qho enzyme koom nrog hauv DNA kho. Nws ua tawm tsam cov qog nqaij hlav hauv cov neeg muaj kab mob BRCA 1 lossis BRCA 2 kev hloov pauv, uas suav nrog qee cov qog nqaij hlav zes qe menyuam, mis thiab prostate. Thaum Lub Kaum Ob Hlis 2014, olaparib tau pom zoo rau kev siv los ua tus neeg sawv cev los ntawm EMA thiab FDA. Kev pom zoo ntawm FDA yog nyob rau hauv kev tua kab mob BRCA mutated (gBRCAm) siab heev ntawm zes qe menyuam mob uas tau txais peb lossis ntau tshaj cov kab mob ua ntej ntawm cov kws khomob.

0010010 nbsp;

0010010 nbsp;

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov hu rau peb!

0010010 nbsp;

0010010 nbsp;

Cov khoom hauv qab patent yog muab rau R 0010010 amp; D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: olaparib cas 763113-22-0, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

• Tug: 1- (Cyclopropylcarbonyl) piperazine Hydrochloride CAS TSIS: 1021298-67-8
• Tom ntej: 3- (2-chloropyrimidin-4-yl) -1-methylindole CAS 1032452-86-0