Hu rau:Errol Zhou (Mr.)
Tel: ntxiv 86-551-65523315
Mobile/WhatsApp: ntxiv 86 17705606359
QQ:196299583
Skype:lucytoday@hotmail.com
Email:sales@homesunshinepharma.com
Ntxiv:1002, Huanmao Tsev, No.105, Mengcheng Txoj kev, Hefei Lub zos, 230061 Tuam Tshoj
CAS Nr .: 1350514-68-9
Cov mis mos molecular: C38H50N6O9S
Molecular Luj: 766.90300
EINECS NO: NA
MDL Nr.: MFCD25976700
Product Description:
Khoom npe: MK5172 CAS NO: 1350514-68-9
Synonyms:
MK-5172||MK5172;
(1aR,5S,8S,10R,22aR)-5-tert-butyl-N-((1R,2S)-1-{[(cyclopropylsulfonyl)amino]carbonyl}-2-vinylcyclopropyl)-14-methoxy-3, 6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10 ,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide;
(1R,18R,20R,24S,27S)-N-{(1R,2S)-1-[(Cyclopropylsulfonyl)carbamoyl]-2-vinylcyclopropyl}-7-methoxy-24-(2-methyl-2-propanyl) 22,25-dioxo-2,21-dioxa-4,11,23,26-tetraazapentacyclo[24.2.1.03,12.05,10.018,20]nonacosa-3,5,7,9,11-pentaene-27-carboxamide , poov tshuaj ntsev;
Tshuaj& Lub cev muaj zog:
Cov tsos mob: Dawb mus rau dawb dawb
Kev Ntsuas: ≥99.0%
Qhov ceev: 1.38 ± 0.1 g / cm3 (Predicted)
Cia Temp: kaw hauv qhuav, Khaws rau hauv lub freezer, qis dua -20 ℃
Ib qho azamacrocyclic compound uas yog tus kab mob siab C protease inhibitor siv nrog elbasvir (hauv lub npe Zepatier) rau kev kho mob HCV genotypes 1 lossis 4 tus kab mob hauv cov neeg laus. Grazoprevir (MK-5172) yog ib qho kev xaiv inhibitor ntawm kab mob siab C NS3/4a protease nrog kev ua haujlwm dav thoob plaws genotypes thiab resistant variants, nrog Kis ntawm 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt25a), 0. (gt2b), 0.90 nM (gt3a), feem.
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
Cov khoom raws li patent muaj rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.
Cim npe nrov: mk5172 cas 1350514-68-9, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, hauv Tshuag
