Macitentan CAS TSIS TAU: 441798-33-0

Khoom Piav Qhia

Khoom Npe: Macitentan CAS TSIS TAU: 441798-33-0

Txhais:

5- (4-bromophenyl) -6- [2- (5-bromopyrimidin-2-yl) oxyethoxy] -N- (propylsulfamoyl) pyrimidin-4-amine;

N- [5- (4-Bromophenyl) -6- {2 - [(5-bromo-2-pyrimidinyl) oxi] ethoxy} -4-pyrimidinyl] -N' - propylsulfuric diamide;

Sulfamide, N- [5- (4-bromophenyl) -6- [2 - [(5-bromo-2-pyrimidinyl) oxi] ethoxy] -4-pyrimidinyl] -N' - propyl- ;

Macitentan;

Actelion-1;

Opsumit;

Tshuaj& Lub cev nqaij daim tawv

Zog: Cov hmoov dawb dawb

Ntsuas: ≥ 99. 0%

Ntom: 1. 675 g / cm 3

Boiling point: 692. 4 ° Miv 760 mmHg

Flash Point: 372. 5 ℃

Macitentan (lub npe lag luam Opsumit) yog endothelin receptor antagonist (ERA) pom zoo rau kev kho mob ntsws pulmonary arterial hypertension (PAH). Lwm qhov ob lub ERA kev lag luam li ntawm 2014 yog bosentan thiab ambrisentan. Macitentan yog dual ERA, lub ntsiab lus nws ua raws li kev thaiv kev ntawm ob endothelin (ET) receptor subtypes, ETA thiab ETB. Txawm li cas los xij, macitentan muaj qhov 50-fold nce xaiv rau ETA subtype piv rau ETB subtype. Cov tshuaj tau txais kev pom zoo los ntawm Asmeskas Cov Khoom Noj thiab Tshuaj (FDA) Lub Kaum Hlis 13, 2013.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov hu rau peb!

Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: macitentan cas tsis: 441798-33-0, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

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