Lonafarnib CAS 193275-84-2

Khoom Qhia:

Lub Npe Khoom Muag: Lonafarnib CAS TSIS TAU: 193275-84-2

Txhais:

1-PiperidinecarboxaMide, 4- [2- [4- [(11R) -3,10-dibroMo-8-chloro-6;

[14C] -Lonafarnib;

Tshuaj& Cov Khoom Uas Lub Cev:

Zog: Dawb rau beige hmoov

Ntsuas: ≥99.0%

Qhov ceev: 1.536

Cia Lub Sij Hawm Cia.: -20 ℃

Flash Point: 383.5 ℃

Lub Ntsiab Kub: 710.4 ℃ ntawm 760mmHg

Melting point: 214.5-215.9 ° (monohydrate); mp 222-223 °

Cov Ntaub Ntawv Kev Nyab Xeeb:

Daim Ntawv Qhia Txog Kev Ceeb Toom: P305 + P351 + P338

Lub Cim: GHS07

Kos Npe: Lo Lus Ceeb Toom

Cov Lus Tshaj Tawm: H315; H319; H335

Lonafarnib yog ib qho farnesyltransferase inhibitor (FTI) uas tseem tab tom tshawb fawb hauv tib neeg kev sim tshuaj raws li kev kho mob rau tus mob progeria.

Lonafarnib yog hluavtaws tricyclic derivative ntawm carboxamide nrog cov khoom antineoplastic. Xws li, nws yog siv feem ntau rau kev kho mob cancer. Rau cov neeg muaj progeria, kev tshawb fawb pom tau tias cov tshuaj txo qis kev kis tus mob stroke thiab hloov ischemic nres, thiab qhov muaj ntau thiab ntau zaus ntawm mob taub hau thaum noj cov tshuaj. Lub sijhawm II kev kuaj mob tau ua tiav rau xyoo 2012, uas tau qhia tias ib qho dej cawv ntawm cov tshuaj uas suav nrog lonafarnib thiab ob yam tshuaj ntxiv, tau ntsib cov chaw kho mob ua tau zoo kawg uas tau txhim kho qhov siab thiab txo qis kev nruj ntawm cov pob txha ntawm cov neeg mob progeria.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: lonafarnib cas 193275-84-2, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

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