IPI 549 CAS 1693758-51-8

Khoom Piav Qhia:

Khoom Lub Npe: IPI 549 CAS TSIS TAU: 1693758-51-8

Lub ntsiab lus:

Pyrazolo [1,5-a] pyrimidine-3-carboxamide, 2-amino-N-[(1S) -1- [1,2-dihydro-8- [2- (1-methyl-1H-pyrazol-4-] yl) ethynyl] -1-oxo-2-phenyl-3-isoquinolinyl] ethyl]-;

Pyrazolo [1,5-a] pyrimidine-3-carboxamide, 2-amino-N-[(1S) -1- [1,2-dihydro-8- [2- (1-methyl-1H-pyrazol-4-] yl) ethynyl] -1-oxo-2-phenyl-3-isoquinolinyl] ethyl]-;

(S) -2-amino-N- (1- (8-((1-methyl-1H-pyrazol-4-yl) ethynyl) -1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl ) ethyl) pyrazolo [1,5-a] pyrimidine-3-carboxamide; IPI-549 (IPI549);

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Khoom

Kev Ntsuas: ≥99.0%

Ceev: 1.37 ± 0.1 g/cm3 (Kwv yees)

PKa: 10.81 ± 0.46 (Kwv yees)

IPI-549, tsim los ntawm InfinityPharmaceuticals, ua haujlwm los ntawm thaiv cov molecule PI3kinase-gamma (PI3chemicalbookkγ) hauv cov tshuaj tiv thaiv kab mob. Cov txiaj ntsig, tshaj tawm hauv Xwm Xwm xyoo 2016, pom tias thaiv cov tshuaj no hloov pauv qhov sib npaug ntawm cov tshuaj tiv thaiv kab mob no thiab txhawb nqa kev ua kom tiv thaiv qog qog nqaij hlav. IPI-549 yog xaiv cov tshuaj tiv thaiv phosphoinositol 3 kinase (PI3Kγ). PI3Kγ inhibitors tuaj yeem siv los txhim kho kev muaj peev xwm kho mob rau cov kab mob autoimmune. IPI-549, tsim los ntawm Infinity Pharmaceuticals, ua haujlwm los ntawm kev thaiv PI3 kinase-gamma (PI3Kγ) cov qauv hauv cov tshuaj tiv thaiv cov hlwb, uas tuaj yeem siv ua cov tshuaj reagent ntawm tes.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: ipi 549 cas 1693758-51-8, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

• Tug: LJN 452 CAS 1383816-29-2
• Tom ntej: TP 235 CAS 443104-02-7