Hypericin CAS 548-04-9

Product Description:

Khoom npe: Hypericin CAS NO: 548-04-9

Synonyms:

MYCOPOPHYRIN;

CYCLO-WERROL;

HYPERICUM liab;

Tshuaj& Lub cev muaj zog:

Cov tsos mob: Liab-xim anthraquinone-derivative

Kev Ntsuas: ≥99.0%

Qhov ceev: 1.915 g / cm3

Boiling Point: 1020.3 ℃ ntawm 760 mmHg

Melting Point: 299-301 ℃

Flash Point: 584.6 ℃

Refractive Index: 2.13

Cia Cia: Cia ntawm +4 ℃

Sensitive: Lub teeb Sensitive

Cov ntaub ntawv kev nyab xeeb:

Cov Lus Qhia Txog Kev Nyab Xeeb: S22-S36

PIB: 2914700090

WGK Germany: 3

RIDADR: UN 2811

Risk Nqe: R22

Hazard Code: XIV

Hypericin yog ib qho naphthodianthrone, xim liab-xim anthraquinone-derivative, uas, ua ke nrog hyperforin, yog ib qho tseem ceeb ntawm cov khoom tseem ceeb ntawm Hypericum (Saint John' s wort). Hypericin ntseeg tau tias ua cov tshuaj tua kab mob, tshuaj tua kab mob thiab tsis yog tshwj xeeb kinase inhibitor. Hypericin tuaj yeem cuam tshuam qhov kev ua ntawm cov enzyme dopamine β-hydroxylase, ua rau kom nce qib dopamine, txawm hais tias muaj peev xwm txo qis norepinephrine thiab epinephrine.

Nws tau pib ntseeg tias kev ua haujlwm ntawm cov tshuaj tiv thaiv kev nyuaj siab ntawm hypericin yog vim inhibition ntawm monoamine oxidase enzyme. Cov kua txiv hmab txiv ntoo ntawm Hypericum yog qhov tsis muaj zog inhibitor ntawm MAO-A thiab MAO-B. Kev rho tawm hypericin tsis tso tawm cov haujlwm no, tab sis nws muaj qee qhov kev sib raug zoo rau NMDA receptors. Cov ntsiab lus no nyob rau hauv cov kev taw qhia tias lwm cov neeg koom tes yog lub luag hauj lwm rau MAOI nyhuv. Txoj kev ntseeg tam sim no yog tias cov txheej txheem ntawm kev ua haujlwm antidepressant yog vim qhov inhibition ntawm reuptake ntawm qee yam neurotransmitters.

Qhov loj chromophore system nyob rau hauv lub molecule txhais tau hais tias nws muaj peev xwm ua rau photosensitivity thaum noj ntau tshaj qhov pib. Photosensitivity feem ntau pom nyob rau hauv cov tsiaj uas tau tso cai rau graze ntawm St. John's Wort. Vim hais tias hypericin accumulates nyiam nyob rau hauv cov ntaub so ntswg cancer, nws kuj yog siv los ua ib qho kev qhia ntawm cov qog nqaij hlav cancer. Tsis tas li ntawd, hypericin yog nyob rau hauv kev tshawb fawb raws li ib tug neeg sawv cev nyob rau hauv photodynamic kho, uas yog ib tug biochemical absorbed los ntawm ib tug kab mob yuav tsum tau tom qab qhib nrog spectrum tshwj xeeb lub teeb los ntawm tshwj xeeb teeb los yog laser qhov chaw, rau kev kho mob lub hom phiaj. Cov tshuaj tua kab mob thiab tshuaj tua kab mob ntawm hypericin kuj tseem ntseeg tau tias tshwm sim los ntawm nws lub peev xwm rau kev yees duab-oxidation ntawm cov hlwb thiab cov kab mob kis.

Hypericin muab los ntawm polyketides cyclisation.

Lub biosynthesis ntawm hypericins yog nyob rau hauv txoj kev polyketide qhov twg cov octaketide saw mus los ntawm cov txheej txheem ntawm cylizations thiab decarboxylations tsim emodin anthrone uas ntseeg tau tias yog cov precursors ntawm hypericin. Oxidization tshwm sim tawm los protoforms uas tom qab ntawd hloov mus rau hauv hypericin thiab pseudohypericin. Cov tshuaj tiv thaiv no yog photosensitive thiab tshwm sim nyob rau hauv raug lub teeb thiab siv cov enzyme Hyp-1.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom raws li patent muaj rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: Hypericin CAS 548-04-9, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, hauv Tshuag

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