GSK 561679A CAS 885220-61-1

Khoom Piav Qhia:

Khoom Lub Npe: GSK 561679A CAS TSIS TAU: 885220-61-1

Lub ntsiab lus:

3- (4-Methoxy-2-methylphenyl) -2,5-dimethyl-N-[(1S) -1- (3-methyl-1,2,4-oxadiazol-5-yl) propyl] pyrazolo [1, 5-a] pyrimidin-7-amine; Verucerfont;

CPD1230;

GSK561679;

Tshuaj& Lub Cev Muaj Zog:

Tsos: Hmoov

Kev Ntsuas: ≥99.0%

Ceev: 1.29

PKa: 4.78 ± 0.40 (kwv yees)

Verucerfont (GSK-561,679) yog tshuaj tsim los ntawm GlaxoSmithKline uas ua raws li corticotropin tso cov tshuaj hormone receptor 1 (CRF1) antagonist. Corticotropin-tso tawm qhov tseem ceeb (CRF), tseem hu ua corticotropin-tso cov tshuaj hormone, yog endogenous peptide hormone uas tau tso tawm hauv kev teb rau ntau yam ua rau muaj kev ntxhov siab, thiab qhib ob lub corticotropin tso cov tshuaj receptors CRF1 thiab CRF2. Qhov no yog qhov ua rau tso tawm corticotropin (ACTH), lwm yam tshuaj uas koom nrog hauv lub cev kev teb rau kev ntxhov siab.

Verucerfont thaiv cov CRH-1 tus txais, thiab yog li txo ACTH tso tawm tom qab kev nyuaj siab ntev. Nws tseem tab tom tshawb fawb raws li qhov muaj peev xwm kho tau rau kev quav dej quav cawv, vim tias kev nyuaj siab nyob ntev yog feem ntau ua rau muaj kev txhim kho kev quav dej quav cawv thiab rov qab ua kom rov zoo cawv. Nws tau pom tias muaj txiaj ntsig zoo hauv kev tshawb fawb tsiaj tab sis tsis tau sim hauv tib neeg.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: gsk 561679a cas 885220-61-1, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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