Flavoxate Hydrochloride CAS 3717-88-2

Khoom Piav Qhia:

Khoom Lub Npe: Flavoxate hydrochloride CAS TSIS TAU: 3717-88-2

Lub ntsiab lus:

2-piperidin-1-ylethyl 3-methyl-4-oxo-2-phenylchromene-8-carboxylate, hydrochloride;

1-piperidineethanol, 3-methyl-4-oxo-2-phenyl-4h-1-benzopyran-8-carboxylate, h;

3-methyl-4-oxo-2-phenyl-4h-1-benzopyran-8-carboxylicaci2-piperidinoethyl;

Tshuaj& Lub Cev Muaj Zog:

Tsos: Dawb dawb

Kev Ntsuas: ≥99.0%

Ceev: 1.203g/cm3

Kub Point: 564.1 ℃ ntawm 760 mmHg

Melting Point: 232-234 ℃

Flash Point: 294.9 ℃

Cov Ntaub Ntawv Kev Nyab Xeeb:

RTECS: DJ2450000

Nqe Lus Nyab Xeeb: S26

Tus lej HS: 2934999090

Cov Ntsiab Lus Risk: R22; R36/37/38

Cov lej phom sij: Xn

Kev Tshaj Tawm Kev Nyab Xeeb: H302; H315; H319; H335

Cim: GHS07

Lo Lus Teeb: Ceeb Toom

Cov Lus Ceeb Toom Ceev: P261; P305, P351, P338

Ua kom cov leeg nruj. Siv los ua antispasmodic; hauv kev kho mob tso zis tso quav.

Flavoxate Hydrochloride (DW-61 Hydrochloride) yog muscarinic AChR antagonist siv nyob rau hauv ntau yam kab mob tso zis thiab raws li antispasmodic.Target: mAChRFlavoxate txav chaw [3H] nitrendipine ntawm Ca2+ raws qhov chaw khi nrog IC50 ntawm 254 μM. Flavoxate (& gt; 10 μM) suppresses carbachol-induced contractions in isolated rat detrusor strips nrog pD tus nqi ntawm 4.55. Flavoxate (& gt; 10 μM) suppresses Ca2+-induced contractions in isolated rat detrusor strips with pIC50 tus nqi ntawm 4.92. Flavoxate (0.01 μM? 10 μM) inhibits CAMP tsim nyob rau hauv ib qho kev xav-nyob yam nyob rau hauv daim nyias nyias los ntawm nas striatum thiab cerebral cortex, qhov kev txiav txim uas tau tshem tawm tag nrho los ntawm pretreating daim nyias nyias nrog kab mob pertussis (PTX) [3] .Flavoxate (10mg) /kg) suppresses ob qhov pib, nce nrawm phasic contraction (theem 1) thiab tonic contraction (theem 2) contractions rau tib yam li nas. Flavoxate (10mg/kg) tshem tawm txoj hlab ntaws uas tsis ua rau muaj qhov hloov pauv ntawm qhov sib cog ntawm cov nas. Flavoxate (3 mg/kg) tshem tawm qhov ua haujlwm tsis zoo ntawm lub paj hlwb thiab cuam tshuam nrog lub zais zis sib luag li 10 feeb yam tsis hloov pauv lub hauv paus vesical siab hauv nas. ICV-txhaj tshuaj (50 txog 200 μg/nas) lossis IT-txhaj (100 txog 200 μg/nas) Flavoxate tshem tawm qhov ua rau lub zais zis sib thooj thaum thiab tom qab txhaj tshuaj rau tsib mus rau 15 feeb hauv kev txhaj tshuaj raws tus nas. Flavoxate (3 mg/kg, iv) tshem tawm kev ua haujlwm zais zis zais zis thiab qhov sib nrug ntau ntawm qhov voiding contractions yog 7.20 min.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: flavoxate hydrochloride cas 3717-88-2, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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