Elexacaftor CAS 2216712-66-0

Product Description:

Khoom npe: Elexacaftor CAS 2216712-66-0

 

Synonyms:

N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

xwv 44

N-[(1,3-Dimethyl-1H-pyrazol-4yl)sulfonyl]-6-[3-(3,3,3-trifluoro-2,2dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)2,2,4-trimethylpropoxy-1-carboxymethylpyrazol-1-yl]

 

 

Chemical & Physical Properties

Qhov tsos: Dawb rau tawm -dawb Khoom

Kev Ntsuas: NLT98%

Melting Point: 206-208 degree

Qhov ceev: 1.38g / cm3

 

 

Daim ntawv thov: Elexacaftor yog ib feem ntawm ib qho ruaj khov -cov ntsiav tshuaj ua ke tsim los ntawm Vertex Pharmaceuticals thiab pom zoo los ntawm US Food and Drug Administration (FDA) rau kev kho cov kab mob cystic fibrosis ntau tshaj, F508del. Nws yog siv ua ke nrog tezacaftor thiab ivacaftor. Elexacaftor thiab tezacaftor ua raws li CFTR (cystic fibrosis transmembrane conductance regulator) kho, thaum ivacaftor ua haujlwm ua CFTR potentiator. Kev sib xyaw ua ke yog txhawm rau txhawm rau txhim kho kev ua haujlwm thiab kev lag luam ntawm cov protein CFTR tsis zoo thiab ua kom cov haujlwm ntawm CFTR ntawm lub xovtooj ntawm tes. Txoj kev loj hlob ntawm elexacaftor sawv cev rau kev kho mob tseem ceeb rau cov neeg mob uas muaj cystic fibrosis, tshwj xeeb tshaj yog cov uas nqa F508del kev hloov pauv.

 

 

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

 

 

 

Cov khoom raws li patent yog muab rau R & D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: elexacaftor cas 2216712-66-0, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, hauv Tshuag

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