Ebastine CAS TSIS: 90729-43-4

Khoom Piav Qhia

Cov Khoom Npe: Ebastine CAS TSIS: 90729-43-4

Txhais:

4- (4-benzhydryloxypiperidin-1-yl) -1- (4-tert-butylphenyl) butan-1-ib;

Ebastinum [Latin];

[14 C] -Ebastine;

saib xyuas pa;

4-diphenylmethoxy-1- [3- (4-tert-butylbenzoyl) propyl] -piperidine;

ebastine;

Kuaj Txiab;

Ebastel;

Estivan;

Ebastin;

Tshuaj& Lub cev nqaij daim tawv

Tsos: dawb rau off-dawb crystalline hmoov

Ntsuas: ≥ 99%

Ntom: 1. 09 g / cm 3

Melting Point: 80-82 ℃

Lub Hauv Boiling Point: 569. 3 ℃ ntawm 760 mmHg

Flash Point: 314. 5 ℃

Kev daws tau: Me ntsis soluble hauv chloroform, methanol.

Ebastine belongs rau cov neeg ua haujlwm zoo thib ob histamine H 1 receptor antagonist. Ib qho cuab yeej tseem ceeb ntawm nws yog tias nws tsis nkag mus rau cov ntshav hlwb kev cuam tshuam. Yog li ntawd, nws muaj peev xwm los thaiv H 1 cov receptor hauv cov ntaub so ntswg uas tsis muaj qee yam kev mob tshwm sim xws li ua kom loog thiab tsaug zog. Ebastine tsuas yog thov rau kev kho mob los ntawm kev ua xua rau rhinitis, pruritus raws li kev ua yeeb yaj kiab raws li lwm txoj tshuaj hauv Decongestant. Thaum nkag mus rau hauv tib neeg lub cev, nws tuaj yeem ua raws li hepatic cytochrome P450 3A 4 kom hloov mus rau ib qho carboxylic acid metabolite, carebastine. Tom qab ib qho yog daim ntawv tseem ceeb hauv vivo. Hauv qee qhov ntau, nws tuaj yeem tiv thaiv T cell proliferation thiab tsim tawm ntawm Th2-hom pro-inflammatory cytokines los ntawm macrophages. Ebastine feem ntau muaj cov khoom ntiag tug muaj kev nyab xeeb tsis ua rau lub hlwb / lub hlwb ntawm lub hlwb tsis zoo thiab ua kom loog, zoo li cov placebo. Txawm li cas los xij, nws tuaj yeem ua rau cov kev mob tshwm sim xws li mob ntawm cov huab cua uas nyob ib ncig ntawm lub qhov ntswg, mob caj pas, kem plab, xeev siab, mob taub hau, thiab mob plab.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: ebastine cas tsis muaj: 90729-43-4, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

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