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Ntxiv:1002, Huanmao Tsev, No.105, Mengcheng Txoj kev, Hefei Lub zos, 230061 Tuam Tshoj
CAS TSIS TAU: 148016-81-3
Cov mis mos molecular: C15H24N4O6S2
Molecular phaus: 420.50400
EINECS NO: Tsis yog
MDL TSIS MUAJ: MFCD02092739
Khoom Piav Qhia:
Khoom Lub Npe: Doripenem CAS TSIS TAU: 148016-81-3
Lub ntsiab lus:
(+)-(4r, 5s, 6s) -6-[(1r) -1-hydro-xyethyl] -4-methyl-7-oxo-3-[[(3s, 5s) -5- [(sulfamoylamino) -methyl] -3-pyrrolidinyl] thio] -1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid;
(4R, 5S, 6S) -6-((R) -1-hydroxyethyl) -4-Methyl-7-oxo-3-((3S, 5S) -5-((sulfaMoylaMino) Methyl) pyrrolidin-3-ylthio ) -1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid;
Doripenem (+)-(4R, 5S, 6S) -6-[(1R) -1-Hydro-xyethyl] -4-methyl-7-oxo-3-[[(3S, 5S) -5 -[(sulfamoylamino) -methyl] -3-pyrrolidinyl] thio] -1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid;
Tshuaj& Lub Cev Muaj Zog:
Tshwm sim: Dawb mus rau cov hmoov dawb
Kev Ntsuas: ≥99.00%
Ceev: 1.59 g/cm3
Kub Point: 694.8 ℃ ntawm 760 mmHg
Melting Point:> 186 ℃ dec.
Flash Point: 374 ℃
Refractive Index: 1.68
Doripenem yog tshuaj tiv thaiv kab mob ultra-broad-spectrum uas tau txhaj tshuaj. Nws yog beta-lactam thiab koom nrog pawg pab pawg ntawm carbapenems. Nws tau tsim los ntawm Shionogi Co. ntawm Nyij Pooj raws li lub npe Finibax xyoo 2005 thiab tab tom ua lag luam sab nraum Nyij Pooj los ntawm Johnson& Johnson. Nws yog qhov tshwj xeeb tshaj tawm tsam Pseudomonas aeruginosa. Daim ntawv ib txwm yog doripenem monohydrate.
Doripenem tuaj yeem siv rau kev kis kab mob xws li: mob plab zom mov, mob ntsws nyob rau hauv lub tsev kho mob, thiab teeb meem sib kis ntawm cov hlab zis suav nrog mob raum nrog septicemia. Doripenem txo cov txheej txheem ntawm kev tsim kho phab ntsa ntawm tes, uas thaum kawg ua rau tshem tawm cov kab mob ntawm cov kab mob sib kis tau zoo.
Nws tau pom zoo tias cov uas ua xua rau doripenem lossis rau txhua hom tshuaj beta-lactam tshuaj tua kab mob xws li cephalosporin lossis lwm yam Carbapenems tsis tau txais doripenem.
Doripenem tau pom zoo los ntawm Tsoom Fwv Teb Chaws Asmeskas Khoom Noj thiab Tshuaj Hauv Lub Kaum Hli 12, 2007, kom raug muag raws li lub npe Doribax. Nws yog tus tswv cuab thib plaub ntawm chav kawm carbapenem tau pom zoo hauv Tebchaws Meskas. Kev ruaj ntseg ntau dua ntawm doripenem hauv cov kua dej sib piv rau cov tswv cuab yav dhau los ntawm chav kawm carbapenem tso cai rau nws los tswj hwm raws li kev tso ntshav dhau 4 teev lossis ntau dua, uas yuav muaj txiaj ntsig zoo hauv kev kho qee yam nyuaj-rau-kho kab mob. Nws tuaj yeem ua rau muaj kev pheej hmoo qis ntawm kev qaug dab peg ntau dua li lwm cov carbapenems.
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.
Cim npe nrov: doripenem cas 148016-81-3, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag
