Donepezil CAS 120014-06-4

Khoom Qhia:

Khoom npe: donepezil CAS TSIS: 120014-06-4

Txhais:

2 - [(1-benzyl-4-piperidyl) methyl] -5,6-dimethoxy-2,3-dihydroinden-1-ib;

2,3-dihydro-5,6-dimethoxy-2 - ((1- (phenylmethyl) -4-piperidinyl) methyl) -1h-inde; n-1-ib;

N-Benzyl-4 - [(5,6-dimethoxy-1-indanon-2-yl) methyl] piperidine;

Tshuaj& Cov Khoom Uas Lub Cev:

Zog: Cov hmoov dawb dawb lossis yuav luag siv lead ua

Ntsuas: ≥98%

Qhov ceev: 1.141g / cm3

Lub Ntsiab Kub: 527.9 ℃ ntawm 760mmHg

Melting Point: 207 ℃

Flash Point: 273.1 ℃

Qhov Taw Qhia Txaus Nruab Nrab: 1.578

Vapor Siab: 3.11E-11mmHg ntawm 25 ℃

Dej Solubility: 2.931 mg / L

Cia: Muab khaws cia ntawm -20 ℃

Cov Ntaub Ntawv Kev Nyab Xeeb:

RIDADR: UN 2811

Cov Lus Ceeb Toom Yuav Muaj: R36 / 37/38

Txoj Cai Kev Nyab Xeeb: Xi

Cov Lus Qhia Kev Nyab Xeeb: S26; S36

Cov Nqe Lus Ceeb Toom: H302+H312+H315+H319+H332+H335

Cov ntawv ceeb toom ua ntej:

P260+P262+P270+P280+P302+P352+P304+P340+P305+P351+P338+P402+P404+P411

Donepezil, ua lag luam nyob rau hauv lub npe lag luam Aricept, yog cov tshuaj siv nyob rau hauv palliative kev kho mob Alzheimer' s kab mob. Donepezil yog siv los txhim kho kev paub thiab kev coj ua ntawm cov neeg muaj Alzheimer' s, tab sis tsis qeeb cov kev vam meej ntawm lossis kho cov kab mob.

Cov kev mob tshwm sim feem ntau suav nrog poob qab los noj mov, plab zom mov chim, raws plab, pw tsaug zog nyuaj, ntuav, lossis mob plab.

Nws tau tsim los ntawm Eisai thiab Pfizer thiab raug muag raws li qhov tsis tshua muaj nqi los ntawm ntau tus neeg muag khoom. Donepezil ua qhov nruab nrab ua yeeb yam thim rov qab acetylcholinesterase inhibitor.Donepezil yog lwm qhov "tsis ua," nruab nrab ua yeeb yam, thim rov qab, tsis ua haujlwm AChEI uas tau pom zoo rau xyoo 1997 rau kev kho mob ntawm mob me-rau-nruab nrab AD thiab dementia. Nws xaiv rau AChE yog 570- rau 1,250-quav uas rau butyrylcholinesterase, thiab nws tseem ua rau pom kev cuam tshuam zoo dua rau lub hlwb AChE dua rau AChE nyob rau hauv qhov nrug.

Acetylcholine yog neurotransmitter koom nrog neural taw thoob plaws lub cev. Donepezil yog qhov thim rov qab acetylcholinesterase inhibitor uas nkag tau yooj yim hla cov ntshav-hlwb teeb meem kom txo qis ntawm acetylcholine. Nws muaj ib nrab-lub neej nyob rau hauv kev ncig ntawm 70 teev. Raws li acetylcholine modulates plasticity, excitability, thiab arousal hauv nruab nrab lub paj hlwb, donepezil feem ntau siv rau hauv kev kho mob Alzheimer tus kab mob txhawm rau txhim kho kev txawj ntse, nco, thiab tus cwj pwm. Ua li no, nws yog txhawm rau tiv thaiv lossis thiav dementia. Kev tshawb fawb txog cov teebmeem no tau zoo sib xws, qhia tau tias ntau cov kev tshawb fawb txog kev kho mob muaj peev xwm ntawm donepezil tau lav.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: donepezil cas 120014-06-4, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

• Tug: DONEPEZIL HYDROCHLORIDE CAS 110119-84-1
• Tom ntej: 1,3,5-Tris (4-bromophenyl) benzene CAS 7511-49-1