Cyproterone Acetate CAS 427-51-0

Khoom Piav Qhia:

Khoom Lub Npe: Cyproterone acetate CAS TSIS TAU: 427-51-0

Lub ntsiab lus:

Cyproterone 17-O-acetate;

Cyproteron acetate;

20-dione, 6-chloro-17-hydroxy-1-alpha, 2-alpha-methylene-pregna-6-diene-3;

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Crystalline Solid

Kev Ntsuas: ≥99.0%

Ceev: 1.27 g/cm3

Kub Point: 525.9 ℃ ntawm 760 mmHg

Melting Point: 200-201 ℃ Cov

Flash Point: 177.6 ℃

Refractive Index: 1.582

Cia Li Cas: 2-8 ℃

Vapor Siab: 3.78E-11mmHg ntawm 25 ℃

Cov Ntaub Ntawv Kev Nyab Xeeb:

RTECS: GZ2230000

Cov Lus Hais Txog Kev Nyab Xeeb: S26-S36

HS Code: 2937290090

WGK Lub Tebchaws Yelemees: 3

Cov nqe lus pheej hmoo: R20/21/22; R40

Cov lej phom sij: Xn, Xi

Cov cawv dawb yog cov tshuaj tiv thaiv androgen; acetate yog ob qho tshuaj tiv thaiv androgen thiab progestogen. Ua ke nrog cov tshuaj estrogen nws tau siv hauv kev kho pob txuv. Cyproterone acetate yog ib qho tshuaj androgen receptor (AR) antagonist nrog IC50 ntawm 7.1 nM, nrog rau qhov tsis muaj zog progesterone receptor agonist nrog kev qaug zog pro-gestational thiab kev ua haujlwm glucocorticoid. Lub Hom Phiaj: Androgen ReceptorCyproterone acetate qhia meej txog cov yam ntxwv tsis zoo, thaum ua ib feem ntawm agonist kuj, qhia kev mob siab rau AR, nrog EC50 ntawm 4.0 μM, ntawm qhov sib piv siab. Hauv qhov muaj 10 nM Testosterone, qis qis ntawm Cyproterone acetate txwv tsis pub T-txhawb nqa cov ntawv ntawm 3XHRE-LUC, tab sis ntawm qhov ntau dua, cov ntawv sau tau txhawb zog. LH qib hauv Cyproterone acetate kho cov nas tsis poob qis dua qib kev kho ua ntej, txawm hais tias lawv tsis nce ntau npaum li cov nas kho nrog 3.2 mg Cyproterone acetate/kg/hnub zoo li cov uas tau txais 0.2 mg Cyproterone acetate/kg/hnub. Cyproterone acetate nthuav tawm cov txiaj ntsig tsis zoo ntawm lub cev hnyav hnyav thiab txo qhov cuam tshuam tseem ceeb ntawm phev suav thiab Ca2+ cov ntsiab lus. SOD thiab GST cov dej num tseem ceeb txo qis ntxiv rau qhov tseem ceeb hauv NO, MDA cov ntsiab lus cuam tshuam txog qhov xwm txheej oxidative ntawm kev kuaj hauv Cyproterone acetate kho cov nas.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: cyproterone acetate cas 427-51-0, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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