Hu rau:Errol Zhou (Mr.)
Tel: ntxiv 86-551-65523315
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CAS TSIS TAU: 1032900-25-6
Cov mis mos molecular: C28H36ClN5O3S
Molecular phaus: 558.13500
EINECS TSIS YOG: 811-457-8
MDL NO: NA
Khoom Piav Qhia:
Khoom Lub Npe: Ceritinib CAS TSIS TAU: 1032900-25-6
Lub ntsiab lus:
5-chloro-N2- (2-isopropoxy-5-methyl-4- (piperidin-4-yl) phenyl) -N4- [2- (propane-2-sulfonyl) phenyl] pyrimidine-2,4-diamine;
Ceritinib (LDK378);
LDK378 || LDK-378;
Tshuaj& Lub Cev Muaj Zog:
Tshwm sim: Tawm dawb dawb
Kev Ntsuas: ≥99.0%
Ceev: 1.251 ± 0.06 g/cm3 (Kwv yees)
Kub Point: 720.7 ± 70.0 ℃ (Kwv yees)
PKa: 10.16 ± 0.10 (Kwv yees)
Flash Point: 389.6 ± 35.7 ℃
Vapor Siab: 0.0 ± 2.3 mmHg ntawm 25 ℃
Index ntawm Refraction: 1.595
Ceritinib (INN, lub npe lag luam Zykadia) yog tshuaj rau kev kho mob tshwj xeeb ntawm kev mob ntsws cancer. Nws yog anaplastic lymphoma kinase (ALK) inhibitor. Nws tau tsim los ntawm Novartis. Nws tau pom zoo thaum lub Plaub Hlis 2014 los ntawm Food and Drug Administration rau kev kho mob ALK-positive metastatic non-small cell lung cancer (NSCLC) hauv cov neeg mob uas ua tsis tiav kho nrog crizotinib. Nws yog qhov muaj txiaj ntsig zoo dua, tab sis muaj tshuaj lom ntau dua, lwm txoj hauv kev rau kev kho tshuaj platinum-based. Ceritinib tau pom ntawm lub cev ntau ntxiv los tiv thaiv ALK, insulin-like growth factor 1 receptor (IGF-1R), thiab ROS1.
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.
Cim npe nrov: ceritinib cas 1032900-25-6, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag