Candesartan Cilexetil CAS 145040-37-5

Khoom Piav Qhia:

Khoom Lub Npe: Candesartan cilexetil CAS TSIS TAU: 145040-37-5

Lub ntsiab lus:

1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-] (2H-tetrazol-5-yl) [1,1' -biphenyl] -4- yl] methyl]-, 1-[[(cyclohexyloxy) carbonyl] oxy] ethyl ester;

Candesantan Cilexetil;

1-(((cyclohexyloxy) carbonyl) oxy) ethylester, (+-)-henyl) -4-yl) methyl);

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Dawb crystalline hmoov

Kev Ntsuas: ≥99.00%

Ceev: 1.37 g/cm3

Kub Point: 843.3 ℃ ntawm 760 mmHg

Flash Point: 463.8 ℃

Refractive Index: 1.665

StorageTemp: -20 ℃ Lub Freezer

Solubility: DMSO: ≥15mg/Ml

Cov Ntaub Ntawv Kev Nyab Xeeb:

Cov Lus Hais Txog Kev Nyab Xeeb: S26; S36

HS Code: 2933990090

Cov Ntsiab Lus Risk: R20/21/22

Cov lej phom sij: Xn, N, T.

WGK Lub Tebchaws Yelemees: 3

RTECS: DD6672500

Ester cov khoom siv; hydrolized hauv vivo rau cov nquag carboxylic acid. Siv nyob rau hauv kev kho mob congestive plawv tsis ua hauj lwm. Antihypertensive tshuaj. Candesartan cilexetil yog cov tshuaj muaj zog, ua tau ntev, thiab xaiv angiotensin II hom 1 receptor AT1 antagonist, candesartan. Nws tau nrawm hydrolyzed rau candesartan thaum lub plab zom mov. Tom qab hydrolysis ntawm candesartan cilexetil rau candesartan thaum lub plab zom mov, candesartan xaiv sib tw nrog angiotensin II rau kev khi ntawm angiotensin II receptor subtype 1 AT1 hauv cov leeg leeg leeg, thaiv angiotensin II-kho cov vasoconstriction thiab ua rau vasodilatation. Tsis tas li ntawd, kev tawm tsam ntawm AT1 hauv cov qog adrenal inhibits angiotensin II-txhawb nqa aldosterone synthesis thiab tso tawm los ntawm adrenal cortex; sodium thiab dej tso tawm ntau ntxiv, tom qab ntawd txo qis hauv cov ntshav thiab ntshav siab. Candesartan cilexetil tuaj yeem siv ua tshuaj tua kab thiab tshuaj nruab nrab. Nws tuaj yeem siv ua raw khoom ntawm cov tshuaj antihypertensive. Candesartan yog angiotensin-receptor blocker (ARB) ， Angiotensin receptor blockers zoo tiv thaiv kev phom sij ntawm kev ua kom renin-angiotensin-aldosterone system uas tshwm sim nrog ntshav siab lossis ntshav qab zib. . Tsis zoo li angiotensin-hloov pauv enzyme (ACE) inhibitors, ARBs tsis muaj qhov tsis zoo ntawm hnoos qhuav. Candesartan tuaj yeem siv los kho ntshav siab, cais ntshav siab, sab laug ventricular hypertrophy thiab ntshav qab zib nephropathy. Nws kuj tseem tuaj yeem siv los ua lwm tus neeg sawv cev rau kev kho mob plawv tsis ua haujlwm, ua haujlwm tsis ua haujlwm, ua rau myocardial infarction thiab kab mob hauv lub plawv.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: candesartan cilexetil cas 145040-37-5, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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