Hu rau:Errol Zhou (Mr.)
Tel: ntxiv 86-551-65523315
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Ntxiv:1002, Huanmao Tsev, No.105, Mengcheng Txoj kev, Hefei Lub zos, 230061 Tuam Tshoj
CAS Tsis Yog: 179324-69-7
Cov Qauv Sib Nqus: C19H25BN4O4
Cov Nqa Molecular: 384.237
EINECS TSIS MUAJ: 605-854-3
MDL TSIS TAU: MFCD05260688
Cov Khoom Qhia:
Khoom npe: Bortezomib CAS 179324-69-7
Txhais:
3-methyl-1 - ((S) -3-phenyl-2- (pyrazine-2-carboxamido) propanamido) butylboronic acid;
B - [(1R) -3-Methyl-1 - [[(2S) -1-oxo-3-phenyl-2 - [(2-pyrazinylcarbonyl) amino] propyl] amino] butyl] boronic Acid;
Tshuaj& Cov Khoom Uas Lub Cev:
Zog: Dawb rau Off-White hmoov
Ntsuas: ≥99.0%
Qhov ceev: 1.214
Melting point: 122-124 ℃
PSA: 124.440
LogP: 2.45
Performance index: 1.564
Kev daws tau: Soluble nyob rau hauv chloroform, dimethyl sulfoxide, ethanol thiab methanol.
Kev Ruaj Ntseg: Hygroscopic thiab Hws noo rhiab
Qeb: Amines, Metabolites& Impurities, Nucleotides, Bases& Lwm yam Reagents,
Cov Ntaub Ntawv Kev Nyab Xeeb:
HS Code: 2934999090
Cov Lus Kev Nyab Xeeb: S26-S36 / 37/39
RIDADR: 3261
RTECS TSIS TAU: ED7771666
Cia:Hygroscopic, -20 ° C Lub freezer, Hauv qab Inert Atmosphere.
Daim ntawv thov:1. [(1R) -3-Methyl-1 - [[(2S) -1-oxo-3-phenyl-2 - [(pyrazinylcarbonyl) amino] propyl] amino] butyl] boronic Acid yog thawj cov tshuaj tiv thaiv kab mob kom raug pom zoo los ntawm Asmeskas FDA rau ntau yam mob myeloma, mob ntshav cancer. Kev thim rov qab tshuaj tiv thaiv ntawm 26S proteasome-ib lub thoob-puab muaj qhov sib luag ntawm cov khoom sib luag pom hauv lub nucleus thiab cytosol ntawm txhua lub hlwb eukaryotic. Lub hom phiaj ubiquitin-proteasome txoj hauv kev.
2. Bortezomib (PS-341) yog lub zog loj 20S proteasome inhibitor nrog Ki ntawm 0.6 nM.
Peb lub Hoobkas tsim khoom siv Bortezomib CAS 179324-69-7, kev siv tshuab paub tab, cov khoom lag luam ruaj khov, cov khoom lag luam zoo.
Cov Ntaub Ntawv Nres: Muaj Hauv Tshuag.
Peb tuaj yeem muab CAS 179324-69-7 daim ntawv pov thawj kev tshuaj xyuas (COA), N - [(1R) -1- (Dihydroxyboryl) -3-methylbutyl] -Nα- (pyrazin-2-ylcarbonyl) -L-phenylalaninamide MOA, Bortezomib ROS, MSDS thiab lwm yam kev txhawb nqa rau koj!
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.
Cim npe nrov: bortezomib cas 179324-69-7, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag
