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Hu rau:Errol Zhou (Mr.)

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APIs thiab Intermediates
Azlocillin Sodium CAS 37091-65-9

Azlocillin Sodium CAS 37091-65-9

CAS TSIS TAU: 37091-65-9
Cov mis mos molecular: C20H22N5NaO6S
Molecular phaus: 483.47300
EINECS TSIS YOG: 253-347-7
MDL TSIS YOG: MFCD00864967

Txhawb tshuaj

Khoom Piav Qhia:

Khoom Lub Npe: Azlocillin sodium CAS TSIS: 37091-65-9

Lub ntsiab lus:

D-alpha-([Imidazolidin-2-on-1-yl] carbonylamino) benzylpenicillin;

Sodium [2S- [2a, 5a, 6b (S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl) carbonyl] amino] phenylacetyl] amino] -4-thia-1-azabicyclo [3.2.0] heptane-2-carboxylate;

Azlocillin sodium ntsev;

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Hmoov

Kev Ntsuas: ≥99.0%

Cia txias: huab cua tsis huv, 2-8 ℃

Solubility: H2O: soluble 50mg/ml

Dej Solubility: Yooj yim soluble hauv dej

Cov Ntaub Ntawv Kev Nyab Xeeb:

Nqe Lus Nyab Xeeb: S36

HS Code: 2942000000

Cov Ntsiab Lus Risk: R42/43

Cov lej phom sij: Xn

Azlocillin yog acylampicillin nrog rau lub ntsej muag dav dav tiv thaiv kab mob. Azlocillin (12.5 μg/mL) kuj tseem tiv thaiv indole -negative thiab -positive Proteus spp., Inhibiting 98 thiab 71%, feem. Azlocillin ua haujlwm ntau dua mezlocillin, ticarcillin, thiab carbenicillin thiab ua haujlwm zoo li BLP-1654 tiv thaiv kev sib cais ntawm P. aeruginosa. Cov acyl sab saw ntawm Azlocillin muaj cov qauv ureido- (urea) tom qab lub npe&"ureidopenicillins &"; lossis, tshwj xeeb tshaj yog," acylureidopenicillins." Hauv vitro cov kev tshawb fawb tawm tsam P. aeruginosa qhia pom tias piperacillin muaj cov haujlwm uas yog ob zaug ntawm azlocillin, 4 zaug ntawm mezlocillin thiab ticarcillin, thiab kwv yees li 8 zaug ntawm carbenicillin. Azlocillin tsim cov kab mob ntev nrog ncua lossis tsis muaj lysis hauv kev tshawb fawb morphologic.Azlocillin muaj MICs ntawm 12.5 μg/mL ntawm Pseudomonas aeruginosa. Azlocillin (3.125 μg/mL) ua rau txo qis kev loj hlob tab sis tsis muaj kab mob tua kab mob ntawm Pseudomonas aeruginosa. Azlocillin txo qis theem pib ua lag luam nrog nce cov tshuaj ntau ntxiv. Ntawm qhov qis dua ntawm tobramycin (0.5 μg/ml), kev sib xyaw ua ke nrog ob qho siab thiab qis ntawm Azlocillin muaj txiaj ntsig zoo dua li cov khoom sib xyaw ntawm Pseudomonas aeruginosa. Rho tawm nrog derepression ntawm AmpC enzyme yog ib rau ob qhov kev sib xyaw ua kom muaj zog tiv taus azlocillin ntau dua li cov uas ua rau muaj kev cuam tshuam ntau ntxiv los yog tsis muaj peev xwm nkag tau. Cov uas muaj secondary-lactamases thib ob feem ntau yog (12/14 tus neeg mob) raug rau ceftazidime ntawm 4 mg/L, tab sis yog cov muaj feem tiv taus Azlocillin (MIC ≥128 mg/L hauv 10/14 tus neeg mob).

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Cim npe nrov: azlocillin sodium cas 37091-65-9, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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