Aureobasidin A CAS 127785-64-2

Product Description:

Khoom npe: Aureobasidin A CAS NO: 127785-64-2

Synonyms:

CycloL-Phe-N-methyl-L-Phe-L-Pro-L{ {8}}aIle-N-methyl-L-Val-L-Leu-N{16 }}methyl- -hydroxy-L-Val-(3R)-D-Hmp--N{25 }}methyl-L-Val{28}};

LY-295337;

Aureobasidin A (9CI);

Chemical Physical Properties:

Cov tsos mob: hmoov

Assay: Ntau dua lossis sib npaug rau 99.0 feem pua

Qhov ceev: 1.19g / cm3

Boiling Point: 1229.1 degree ntawm 760 mmHg

Flash Point: 697.1 degree

Refractive Index: 1.574

Vapor Pressure: 0mmHg ntawm 25 degree

Aureobasidin A yog ib qho cyclic depsipeptide uas yog tsim los ntawm cov kab lis kev cai ntawm Aureobasidium pullulan.Aureobasidin A ua raws li nruj -binding noncompetitive inhibitorof lub enzyme inositol phosphorylceramide synthase (IPC synthase), uas yog ib qho tseem ceeb enzyme rau fungal lipidsphing. Ib qho tshwj xeeb ntawm cov qauv ntawm theaureobasidins yog N-methylation ntawm plaub ntawm xya amide nitrogenatoms. Qhov tsis muaj tautomerism dictated los ntawm N-methylation tuaj yeem ua rau muaj kev ruaj khov kho conformert uas yog zoo li tus xub taub hau, qhov kev xav ntawm biologicallyactive conformation ntawm aureobasidin-A.The pradimycins thiab benanomycins yog naphthacenequinonesthat nyob rau hauv lub bind. muaj Ca2 ntxiv rau cuam tshuam cov cell membrane hauv cov kab mob fungi. Ob leeg ua tau zoo nyob rau hauv vitro thiab hauv vivo kev tiv thaiv Candida spp. thiab C. neoformans soj ntsuam cais.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom raws li patent yog muab rau RD lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: aureobasidin a cas 127785-64-2, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, hauv Tshuag

• Tug: Atpenin A5 CAS 119509-24-9
• Tom ntej: Fidaxomicin CAS 873857-62-6