Atazanavir CAS 198904-31-3

Khoom Piav Qhia:

Khoom Lub Npe: Atazanavir CAS TSIS TAU: 198904-31-3

Lub ntsiab lus:

methylN-[(2S) -1- [2-[(2S, 3S] -2-hydroxy-3-[[(2S] -2- (methoxycarbonylamino) -3,3-dimethylbutanoyl] amino] -4-phenylbutyl] -2-[(4-pyridin-2-ylphenyl) methyl] hydrazinyl] -3,3-dimethyl-1-oxobutan-2-yl] carbamate;

Zrivada;

UNII-QZU4H47A3S;

Tshuaj& Lub Cev Muaj Zog:

Tshwm sim: Crystalline khoom

Kev Ntsuas: ≥99.0%

Ceev: 1.178g/cm3

Melting Point: 207-209 ℃

Refractive Index: 1.562

Atazanavir, muag raws li lub npe lag luam Reyataz, yog cov tshuaj tiv thaiv kab mob tiv thaiv kab mob protease inhibitor (PI). Ib yam li lwm yam tshuaj tiv thaiv kab mob antiretrovirals, nws tau siv los kho tus kab mob tib neeg tsis muaj peev xwm tiv thaiv kab mob (HIV).

Atazanavir yog qhov txawv ntawm lwm PIs uas nws tuaj yeem muab ib zaug ib hnub (ntau dua li xav tau ntau koob tshuaj ib hnub) thiab muaj kev cuam tshuam tsawg dua rau tus neeg mob' lipid profile (cov roj (cholesterol) thiab lwm yam tshuaj muaj roj hauv cov ntshav). Zoo li lwm yam tshuaj tiv thaiv kab mob protease, nws tsuas yog siv ua ke nrog lwm yam tshuaj HIV.Lub Koom Haum Saib Xyuas Khoom Noj thiab Tshuaj (FDA) pom zoo atazanavir thaum Lub Rau Hli 20, 2003. Atazanavir yog thawj PI pom zoo rau noj ib hnub ib zaug, thiab tseem zoo li tsawg dua yuav ua rau lipodystrophy thiab nce cov roj cholesterol raws li cov kev mob tshwm sim. Nws kuj tseem yuav tsis tuaj yeem tiv taus nrog lwm PIs. Thaum txhawb nqa nrog ritonavir nws yog qhov sib npaug hauv lub zog rau lopinavir rau siv hauv kev kho mob khaws cia hauv cov neeg mob uas muaj qib tshuaj tiv thaiv kab mob, txawm hais tias txhawb nrog ritonavir txo cov txheej txheem zom zaub mov zoo ntawm atazanavir.

Nws nyob ntawm World Health Organization' Cov Npe Ntawm Cov Tshuaj Tseem Ceeb, cov tshuaj tseem ceeb tshaj plaws uas xav tau hauv kev noj qab haus huv.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: atazanavir cas 198904-31-3, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

• Tug: 2,4,6-Triaminopyrimidine CAS 1004-38-2
• Tom ntej: Des-N- (methoxycarbonyl) -L-tert-leucine Bis-Boc Atazanavir CAS 198904-86-8