Asciminib CAS 1492952-76-7

Khoom Qhia:

Cov Khoom Npe: asciminib CAS TSIS: 1492952-76-7

Txhais:

ABL001;

ASCIMINIB;

ASCIMINIB DAWB XWB;

Tshuaj& Cov Khoom Uas Lub Cev:

Zog: Crystalline khoom

Ntsuas: ≥98.0%

Qhov ceev: 1.5 ± 0.1 g / cm3

Lub Ntsiab Kub: 631.7 ± 55.0 ℃ ntawm 760 mmHg

Flash Point: 335.8 ± 31.5 ℃

Qhov Taw Qhia Txaus Nruab Nrab: 1.662

Cia Li Cas: -20 ℃

Asciminib, tseem hu ua ABL001, yog ib qho muaj zog tag nrho cov roj ntsha ntawm BCR-ABL. ABL001 tiv thaiv kev rov tshwm sim ntawm tus kabmob tiv thaiv thaum muab nrog nilotinib hauv vivo murine qauv ntawm tus mob ua kom tsis muaj ntshav ntau. Cov kev tshawb fawb ntawm tes nthuav tawm qhia tias ABL001 xaiv yam tsis pub muaj kev loj hlob ntawm CML thiab Ph + Txhua lub hlwb nrog lub peev xwm nyob ntawm 1-10nM ntau ABL001 tau raug tshuaj xyuas rau kev ua rau tiv thaiv kev sib hloov kuaj pom thiab pom tau tias muaj siab nyob rau qhov tsis muaj nM ntau. Hauv KCL-22 nas xenograft tus qauv, ABL001 tso tawm muaj hwj chim los tiv thaiv cov qog ua kom tiav nrog cov qog ua kom tiav thiab tau pom meej meej qhov tseeb-nyob sib tshuam nrog pSTAT5 inhibition.

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam hauv qab patent yog muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tau txiav txim siab nrog cov neeg yuav khoom.

Cim npe nrov: asciminib cas 1492952-76-7, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

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