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APIs thiab Intermediates
3 - ((R) -1- (2,6-dichloro-3-fluorophenyl) ethoxy) -5-bromopyridin-2-amine CAS 1448326-33-7

3 - ((R) -1- (2,6-dichloro-3-fluorophenyl) ethoxy) -5-bromopyridin-2-amine CAS 1448326-33-7

CAS TSIS TAU: 1448326-33-7
Cov Qauv Nqaij: C13H10BrCl2FN2O
Molecular Luj: 380.04
EINECS TSIS MUAJ: N / A
MDL TSIS TAU: MFCD28099329

Txhawb tshuaj

Khoom Qhia:

Khoom npe: 3 - ((R) -1- (2,6-dichloro-3-fluorophenyl) ethoxy) -5-bromopyridin-2-amine CAS TSIS: 1448326-33-7

Txhais:

5-Bromo-3 - [(1S) -1- (2,6-dichloro-3-fluorophenyl) ethoxy] -2-pyridinamine;

(S) -5-bromo-3- (1- (2,6-dichloro-3-fluorophenyl) ethoxy) pyridin-2-amine;

Tshuaj& Cov Khoom Uas Lub Cev:

Zog: cov hmoov dawb dawb

Ntsuas:99.0%

Qhov ceev: 1.6g / cm3

Lub Ntsiab Lus Boiling: 423.4ntawm 760 mmHg

Flash Point: 209.9



Crizotinib nrab.

Crizotinib yog ob qho kev coj ua me me molecule tyrosine kinase receptor inhibitor tsom rau mesenchymal-epithelial kev hloov pauv (MET) thiab ALK. Nws lub hom phiaj ntawm kev nqis tes ua hauv NSCLC yog ALK tyrosine Acid kinase receptor. Zoo ib yam li EGFR inhibitor gefitinib, crizotinib inhibits kev ua haujlwm ntawm kinase los ntawm kev cuam tshuam ntawm txoj kev khi ntawm ALK kinase thiab ATP hauv NSCLC thiab autophosphorylation tom qab ua ke ntawm ob, yog li txo kinase kev ua si thiab ua si tawm tsam cov qog ua haujlwm.


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Cim npe nrov: 3 - ((r) -1- (2,6-dichloro-3-fluorophenyl) ethoxy) -5-bromopyridin-2-amine cas 1448326-33-7, tuam ntxhab, lwm tus neeg, Hoobkas, yuav, hauv Tshuag

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