3α-hydroxy-5α-cev xeeb tub-20-ib CAS 516-54-1

Khoom Piav Qhia:

Khoom Lub Npe: 3α-hydroxy-5α-cev xeeb tub-20-ib CAS TSIS: 516-54-1

Lub ntsiab lus:

(3α) -Allopregnanolone;

Pregnan-20-ib, 3-hydroxy-, (3α, 5α)-;

3alpha-hydroxy-5alpha-cev xeeb tub-20-ib;

Tshuaj& Lub Cev Muaj Zog:

Tsos: Dawb dawb

Kev Ntsuas: ≥98.0%

Ceev: 1.053g/cm3

Kub Point: 431.2 ℃ ntawm 760mmHg

Flash Point: 183.9 ℃

Refractive Index: 1.524

Kev Cia Cia: Khaws ntawm RT

Vapor Siab: 0.0 ± 2.3 mmHg ntawm 25 ℃

Dej Solubility: chloroform: 20 mg/mL, ntshiab, tsis muaj xim

Cov Ntaub Ntawv Kev Nyab Xeeb:

Cov Lus Hais Txog Kev Nyab Xeeb: S22; S24/25

WGK Lub Tebchaws Yelemees: 3

RTECS: TU4383000

F: 10

Allopregnanolone (ALLO), tseem hu ua 3α-hydroxy-5α-cev xeeb tub-20-ib lossis 3α, 5α-tetrahydroprogesterone (3α, 5α-THP), yog endogenous inhibitory cev xeeb tub neurosteroid. Nws tau tsim tawm los ntawm progesterone, thiab yog qhov muaj txiaj ntsig zoo allosteric modulator ntawm kev ua ntawm gamma-amininobutyric acid (GABA) ntawm GABAA tus txais. Allopregnanolone muaj cov txiaj ntsig zoo ib yam li lwm qhov kev hloov pauv allosteric zoo ntawm GABA kev ua ntawm GABAA tus neeg txais khoom xws li benzodiazepines, suav nrog kev ntxhov siab, sedative, thiab anticonvulsant activity.

Endogenously tsim allopregnanolone ua lub luag haujlwm tseem ceeb hauv kev kho mob neurophysiological los ntawm kev kho GABAA tus txais thiab hloov kho qhov kev txiav txim ntawm ntau qhov zoo allosteric modulators thiab agonists ntawm GABAA receptor. 21-hydroxylated derivative ntawm qhov sib xyaw no, tetrahydrodeoxycorticosterone (THDOC), yog endogenous inhibitory neurosteroid nrog cov khoom zoo sib xws rau cov allopregnanolone, thiab 3β-methyl analogue ntawm allopregnanolone, ganaxolone, tab tom txhim kho kho mob vwm thiab lwm yam mob, suav nrog -traumatic stress disorder (PTSD).

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: 3α-hydroxy-5α-cev xeeb tub-20-ib cas 516-54-1, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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