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CAS Nr: 41404-58-4
Cov mis mos molecular: C5H3BrFN
Molecular Luj: 175.99
EINECS NO:629-269-8
MDL Nr.: MFCD00234011
Product Description:
Lub npe khoom: 2-bromo-5-fluoropyridine CAS 41404-58-4
Synonyms:
2-bromo-5-fluoro pyridine;
3-fluoro-6-bromopyridine;
Chemical & Physical Properties
Tsos: Yellowish crystal
Kev Ntsuas: 99% +
Kub taw tes: 80-83 degree /44 mmHg
Melting point: 30-31 degree
Flash point: 100 degree
Ceev: 1.7 07 ± 0.06g / cm3
Pka: {{0}}.63±0.10
Refractive Index: 1.5396
Daim ntawv thov
Bromo-5-fluoropyridine yog siv nyob rau hauv lub synthesis ntawm mGluR5 antagonist rau kev kho mob ntawm neuropathic mob.
2-Bromo-5-fluoropyridine tuaj yeem siv rau hauv kev sib txuas ntawm cov hauv qab no:
(1) 5-fluoro-2-phenylpyridine ntawm Suzuki coupling cov tshuaj tiv thaiv nrog phenylboronic acid
(2) 5-fluoro-2-(p-tolyl) pyridine ntawm Suzuki coupling cov tshuaj tiv thaiv nrog p-tolylboronic acid
Nws tuaj yeem ua rau palladium-catalyzed homo-coupling cov tshuaj tiv thaiv kom muab qhov sib thooj biaryl. Nws tuaj yeem ua haujlwm hauv palladium-catayzed -arylation ntawm esters ua rau 4-pyridylcarboxypiperidines.
Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!
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Cim npe nrov: 2-bromo-5-fluoropyridine cas 41404-58-4, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, hauv Tshuag