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APIs thiab Intermediates
2-bromo-5-fluoropyridine CAS 41404-58-4

2-bromo-5-fluoropyridine CAS 41404-58-4

CAS Nr: 41404-58-4
Cov mis mos molecular: C5H3BrFN
Molecular Luj: 175.99
EINECS NO:629-269-8
MDL Nr.: MFCD00234011

Txhawb tshuaj

Product Description:

Lub npe khoom: 2-bromo-5-fluoropyridine CAS 41404-58-4

 

Synonyms:

2-bromo-5-fluoro pyridine;

3-fluoro-6-bromopyridine;

 

Chemical & Physical Properties

Tsos: Yellowish crystal

Kev Ntsuas: 99% +

Kub taw tes: 80-83 degree /44 mmHg

Melting point: 30-31 degree

Flash point: 100 degree

Ceev: 1.7 07 ± 0.06g / cm3

Pka: {{0}}.63±0.10

Refractive Index: 1.5396

 

Daim ntawv thov

Bromo-5-fluoropyridine yog siv nyob rau hauv lub synthesis ntawm mGluR5 antagonist rau kev kho mob ntawm neuropathic mob.

2-Bromo-5-fluoropyridine tuaj yeem siv rau hauv kev sib txuas ntawm cov hauv qab no:

(1) 5-fluoro-2-phenylpyridine ntawm Suzuki coupling cov tshuaj tiv thaiv nrog phenylboronic acid

(2) 5-fluoro-2-(p-tolyl) pyridine ntawm Suzuki coupling cov tshuaj tiv thaiv nrog p-tolylboronic acid

Nws tuaj yeem ua rau palladium-catalyzed homo-coupling cov tshuaj tiv thaiv kom muab qhov sib thooj biaryl. Nws tuaj yeem ua haujlwm hauv palladium-catayzed -arylation ntawm esters ua rau 4-pyridylcarboxypiperidines.

 

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

 

Cov khoom raws li patent yog muab rau R & D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm kawg tsuas yog nrog tus neeg yuav khoom.

Cim npe nrov: 2-bromo-5-fluoropyridine cas 41404-58-4, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, hauv Tshuag

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